introduction:blood-borne infectious agents are one of the main anxieties of blood transfusion organization in all countries. according to who, the blood healthy and blood safety is included ensuring and monitoring of quality and efficiency for all patients requiring blood transfusion. we at the current study intend that survey prevalence hiv ab, hcv ab, hbs ag among blood donors refer to the bl...

The clinical significance of ABO and Rhesus blood group systems has been well documented. The objective of this study was to determine the frequency of ABO and Rhesus blood groups in blood donors in Lahore, Pakistan, with a view to generate data with multipurpose future practicalities in the field of medicine. Blood groups of 3000 blood donors were determined by commercially available standard ...

BACKGROUND AND OBJECTIVES Patient-related blood donors contribute to a significant proportion of the blood units collected in hospital-based blood banks. However, there is some concern on the safety of this kind of donation because of the possible existence of incentives for the donor to conceal deferrable risk factors, thus increasing the risk of donation within the window-period of transfusio...

Cord blood is a sample of blood taken from a newborn baby's umbilical cord.Cord blood is collected because it is rich in stem cells content, such as hematopoietic cells, which can be used to treat hematopoietic and genetic disorders. Cord Blood Transplantation has been used in the treatment of over 80 diseases, including leukemia, lymphoma and anemia. Advantages of Cord Blood Treatment: • ...

Previous clinical evaluation of FK506 in renal transplantation has demonstrated equivalent patient and graft survival when compared with cyclosporine-based regimens. However, lower steroid and anti-hypertensive mediation requirements and lower serum cholesterol levels have been seen in patients receiving FK506. In August, 1991, a prospective, randomized trial was begun, comparing FK506/predniso...

Adverse reactions or lack of response to medications are important concerns for drug development programs. However, faithful predictions of drug metabolism and toxicity are difficult because animal models show only limited translatability to humans. Furthermore, current in vitro systems, such as hepatic cell lines or primary human hepatocyte (PHH) 2-dimensional (2D) monolayer cultures, can be u...

introduction although renal transplantation from cadaver is common, living donors continue to be an important source of transplanted kidneys. recipients of living-donor kidneys demonstrate improved graft survival. in this study, we evaluated the outcomes of renal transplantation from cadaver, related donors and unrelated donors in isfahan. methods we evaluated all of the patients who underwent ...

In a previous report (1978, Proc. Nat. Acad. Sci. USA 75, 3479-3483), we showed that recipient strains of Streptococcusfaecalis excrete a heat-stable substance (sex pheromone) which induces donor cells carrying certain conjugative plasmids to become adherent, generating the cell-to-cell contact necessary for plasmid transfer. Since donors themselves could be induced to aggregate or “clump” by r...

BACKGROUND Natural drug resistance is a major cause of antiviral treatment failure. The characteristics of HIV-1 natural drug resistance-associated mutations in former paid blood donors in Henan Province remain unclear. METHODS One hundred and fifty HIV-1-positive plasma samples were collected. Plasma viral RNA was extracted for pol gene amplification and sequencing. The sequencing results we...

objectives the aim of the present study was to determine the prevalence of anti-hbc and hbsag in blood donors. further, the study aimed to estimate the anti-hbc level at which hbv dna is detected in putative obi cases, as well as to search for mutations in the “a” determinant associated with the non-detection of hbsag in serum. conclusions we observed that as the anti-hbc levels increase, there...