nowadays the most difficult problem in treatment of bacterial infections is the appearance of resistant bacteria to the antimicrobial agents so that the attention is being drawn to other potential targets. in view of the positive findings of phage therapy, many advantages have been mentioned which utilizes phage therapy over chemotherapy and it seems to be a promising agent to replace the antib...

introduction: multi-drug resistant (mdr) p. aeruginosa is constantly increasing and causing severe issues in combatting widely spread health problems. the aim of this study was to assess colistin susceptibility in mdr p. aeruginosa isolates obtained from different infection sites. methods: ninety clinical isolates of p. aeruginosa were collected from different hospitals of the tabriz university...

background& aim: substance abuse is associated with high prevalence of psychiatric disorders including mood disorders (especially depression), personality disorders and psychosis. the purpose of this study was to investigate the effect of methadone and its result on substance induced depression-symptoms among iv drug abusers of kashan prison in 1384. method & materials: this is a semi-experimen...

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background there is a high risk of tuberculosis (tb) infection among injecting drug users (idus). objectives this study aimed to determine the frequency of latent and active tb infection among idus. materials and methods in a cross-sectional study between 2008 and 2009, idus referred to the methadone maintenance treatment (mmt) centers in hamedan-iran, undergone tuberculin skin test (ppd; purif...

descriptive case report of a 42-year old woman with coetaneous vasculitis, and severe abdominal pain, which was led to diagnostic laparotomy. these presentations are probably as a side effect of methocarbamol injection. this is the first report according to our literature search (pubmed, google scholar, isi web of knowledge, proquest, md consult, science direct, scopus) about methocarbamol rela...

context: over the last few decades, extensive efforts have been made worldwide to develop nanomedicine delivery systems, especially via oral route for antidiabetic drugs. absorption of insulin is hindered by epithelial cells of gastrointestinal tract, acidic gastric ph and digestive enzymes. evidence acquisition: recent reports have identified and explained the beneficial role of several struct...

discussion early recognition of dress syndrome is of a particular importance. although rare, in newborn infants with the presence of skin rash, liver involvement, hyper-eosinophilia and lymphadenopathy, dress diagnosis should be highly suspected and prompt intervention including withdrawal of causative drug is required to prevent potentially fatal outcomes. introduction drug rash with eosinophi...

background and objective: implementation of standard methods for accurate detection of bacteria, correct antibiotic susceptibility testing and effective treatment of bacterial infections play important roles in development of public health and prevention of drug resistance. this study aimed to detect bacteria using standard methods and compare the results with the results obtained in teaching h...

evidence acquisition medline, pubmed, ovid and embase were used to search for clinical studies comparing with or without prophylactic use of lamivudine for hbv reactivation in breast cancer patients receiving chemotherapy. outcomes of interest were the rate of hbv reactivation, incidence of hepatitis and incidence of hepatitis attributable to hbv reactivation, severity of hepatitis and severity...