Feeding, eating and deglutition difficulties are key concerns in patients with cardiofaciocutaneous syndrome (CFCS). This study intends to quantify the development of feeding skills from birth adulthood CFCS. Twenty-seven (eight males; mean age: 16.7 ± 8.3 years; median 15 years, age range: 1.5–38 years) molecularly confirmed clinical diagnosis CFCS were prospectively recruited Rare Disease Uni...

Drooling is the involuntary, passive spillage of saliva due to inability handle oral secretions, normally occurring in infants and young children. It considered abnormal have problems with control beyond age 4 years. Physiotherapy treatment including motor stimulation has been regularly used decrease drooling but its effect along dental unknown. Therefore, study was conducted combined physiothe...

Mol. Nutr. Food Res. 2022, 66, 2200182 DOI: 10.1002/mnfr.202200182 A drooling mouse with napkins and cutlery sitting on a clock-based table is waiting for timed feed, representing calorie-restricted hungry condition. And physiological alteration in this showing the left side of picture, which means increased glycogen, fasting blood glucose (the hexagons) insulin keys) levels hepatocyte, indicat...