objective: in recent years, antibiotics have been used widely in the glob to prevent and treat bacterial diseases. they injected into eggs to eliminate pathogens and prevention of egg transmission of disease, but the adverse effects of drugs have always been a major concern. there is little information available about the safety of tetracycline drugs in the embryonated eggs of the birds. the ob...

Background: Due to worldwide increases in the prevalence of antibiotic-resistant bacteria, it is necessary develop an active drug delivery system that can enable therapeutics reach their molecular targets. Maintaining concentration any blood at a certain level for long time critical practice therapy. With increased frequency use, drugs exceeds therapeutic level, leading toxicity or ineffectiven...

Abstract Background and Aims The aged population is constantly increasing, kidney-aging a risk factor for both acute kidney injury (AKI) chronic disease (CKD). Accordingly, CKD major global health problem with an increasing prevalence in older population. Therefore, there urgent need to understand the age-related mechanisms underpinning development during ageing. Recent findings contributed cla...

Objectives: The purpose of this study was to evaluate the effect of low dose doxycycline and atorvastatin on gingival inflammation and alveolar bone loss in an experimental model of periodontitis in rats. Methods: Forty male Sprague Dawley rats were divided into four study groups as follows: (I) experimental periodontitis control, (II) rats with periodontitis treated with low dose atorvastatin...

Objective: In recent years, antibiotics have been used widely in the glob to prevent and treat bacterial diseases. They injected into eggs to eliminate pathogens and prevention of egg transmission of disease, but the adverse effects of drugs have always been a major concern. There is little information available about the safety of tetracycline drugs in the embryonated eggs of the birds. The ob...

Background: The treatment of human brucelosis is controversial. The purpose of this study was to search published clinical trial papers to provide a simple and effective treatment in brucellosis. Methods: Many studies on brucellosis treatment in a twenty- year span from 1993 to 2012 were searched in PubMed, Web of Science (ISI), Scopus, Google Scholar, Magiran, Iranmedex and SID. The studies ...