This study focuses on understanding the impact of intensity-modulated radiotherapy (IMRT) delivery effects when applied to plans generated by commercial treatment-planning systems such as Pinnacle (ADAC Laboratories Inc.) and CadPlan/Helios (Varian Medical Systems). These commercial planning systems have had several version upgrades (with improvements in the optimization algorithm), but the IMR...

At the present, many drugs are used for inhibition of uterine contractions, but the proportions of preterm labors are increasing. Although magnesium sulfate is the most commonly prescribed parenteral tocolytic agent, but its optimal use has yet to be delineated. In this study a high-dose protocol for magnesium sulfate tocolytic therapy was compared with a low-dose regimen. One-hundred patie...

Objective. To determine the dose response and toxicity threshold of micro-collimated X-rays delivered to porcine maculae by a stereotactic radiosurgical system after 270 days. Methods. Twelve eyes of six Yucatan mini-swine were randomized to receive up to 90 Gy to the retina, using an office-based trans-pars plana delivery system. To determine the safety profile of this radiation delivery, opht...

The aim of this study is to compare the dosimetric characteristics of robotic and conventional linac-based SBRT techniques for lung cancer, and to provide planning guidance for each modality. Eight patients who received linac-based SBRT were retrospectively included in this study. A dose of 60 Gy given in three fractions was prescribed to each target. The Synchrony Respiratory Tracking System a...

background: in radiation treatment of moving targets located in thorax region of patient body, the delivered dose does not match with the planned treatment, resulting in some over and under dosage in the tumor volume, as a function of motion magnitude and frequency. several efforts have been done to investigate the target motion effects on dose distribution in the target and surrounding normal ...

To the Editor, Volumetric modulated arc therapy (VMAT) serves as a means for stereotactic hypofractionated treatment of lung tumors [1]. The present authors proposed an efficient VMAT sequence by restricting leaf speeds of a multi-leaf collimator per gantry rotation angle to below 1 mm/degree, thereby reducing the dose delivery time down to 210 s for a D95 prescription dose of 50 Gy in four fra...

A biphasic gastroretentive drug delivery system of fenoverine was developed to maintain constant plasma concentration. The delivery system consisted of a loading-dose tablet and a floating multiple matrix tablet prepared by the direct compression process. The drug release from biphasic GRDDS in 0.1 mol L(-1) HCl and SGF (enzyme free) was sustained over 12 h with buoyant properties. Stability st...

background and objectives: while social network analysis has left a remarkable practical impact in the healthcare field, the potential implication of this methodology in the primary health domain is poorly researched. hence, this study aimed to explore the use and usefulness social network analysis in the context of primary health care. methods: the health volunteers of imam ali health center i...