Previous work described the pharmacokinetics and clinical effects of multidose sublingual triazolam (Halcion; Pharmacia & Upjohn Co, Kalamazoo, Mich). This laboratory study evaluated the hypothesis that incremental dosing of triazolam produces dose-dependent central nervous system depression that is profound and long lasting. Forty-nine healthy adults between the ages of 21 and 39 years, not re...

Introduction 1. The FSA is a statutory consultee to the Environment Agency (EA) and the Scottish Environment Protection Agency (SEPA) for applications to dispose of radioactive material under the Radioactive Substances Act 1993. So that the Agency can comment on the acceptability of proposed discharges, it must estimate the potential doses to consumers of food that contains activity as a conseq...

The present assessment places hormetic dose responses within an historical context, documenting its origin, rejection by the biomedical community during the early decades of the 20 due to its close association with homeopathy and its revitalization during the later decades of the past century as the biomedical and toxicological communities became very interested in low dose effects of drugs and...

In the areas contaminated by radioactive materials due to the Fukushima Daiichi Nuclear Power Station accident, many residents are exposed to radiation through various exposure pathways. Dose assessment is important for providing appropriate protection to the people and clarifying the impact of the accident. The aim of this study is to provide preliminary results of the assessment of radiation ...

background: pet/ct imaging using [18f]-fdg is utilized in clinical oncology for tumor detecting, staging and responding to therapy procedures. essential consideration must be taken for radiation staff due to high gamma radiation in pet/ct and cyclotron center. the aim of this study was to assess the staff exposure regarding whole body and organ dose and to evaluate environment dose in pet/ct an...

background: we have validated the monitor unit calculations from a commercially available treatment planning system (tps) for three intensity modulated radiotherapy (imrt) planning techniques for tangential breast irradiation by using ionization chamber measurements. materials and methods: treatment plans were generated for forty-two breast patients by a forward planned field in field technique...