background and objective: alzheimer’s disease (ad) is a multifactorial disease with debilitating consequences and few therapeutic strategies exist for it. with regard to antioxidant capacity and anti-β-amyloid polymerization potential of ellagic acid, this study was conducted to evaluate the effect of this substance on enhanced acetylcholinesterase reactivity in an experimental model of alzheim...

Much biological experimental data are represented as curves, including measurements of growth, hormone, or enzyme levels, and physical structures. Here we consider the multiple testing problem of comparing two or more nonlinear curves. We model smooth curves of unknown form nonparametrically using penalized splines. We use random effects to model subject-specific deviations from the group-level...

The NF-kappaB-related transcription factor, Dorsal, forms a nuclear concentration gradient in the early Drosophila embryo, patterning the dorsal-ventral (DV) axis to specify mesoderm, neurogenic ectoderm, and dorsal ectoderm cell fates. The concentration of nuclear Dorsal is thought to determine these patterning events; however, the levels of nuclear Dorsal have not been quantified previously. ...

A new species of the luminous roughy fish genus Aulotrachichthys is described based on a single specimen collected from northeastern Taiwan. It differs congeners in having combination characters: striated area caudal peduncle extending posteriorly, slightly beyond middle point peduncle, its length 66.7% caudal-peduncle length; black vertical line caudal-fin base; an overall dark-brown colourati...

Abstract This paper investigates place of articulation shifts involving heterosyllabic C [non-coronal] [coronal] clusters. Such phenomena are found, among other languages, in the diachrony Italiot Greek, where three typologically different historical stages observed: (a) no shifts; (b) dorsal > labial shift; (c) dorsal, coronal shift. Drawing on Rice's (1994) model Place node and markedness ...