نتایج جستجو برای: dolutegravir
تعداد نتایج: 953 فیلتر نتایج به سال:
BACKGROUND Dolutegravir is a powerful, well-tolerated integrase inhibitor with a high genetic barrier to resistance and may thus constitute the backbone of lightened regimens. METHODS This was a monocentric, retrospective study. HIV-1-infected patients receiving dolutegravir as monotherapy (mDGV) or dual therapy (dDGV) were systematically identified. The primary outcome was the proportion of ...
BACKGROUND Little is known about the applicability of dual treatments based on integrase inhibitors. We explored the combination of lamivudine + dolutegravir as an option when switching from standard cART in virologically suppressed patients. METHODS In this prospective cohort we enrolled patients previously switched to 3TC + DTG who were 18 years or older, with no previous resistance mutatio...
In this paper, we consider the glass transition as a kinetic process and establish one universal equation for the pressure coefficient of the glass transition temperature, dTg/dp, which is a thermodynamic characteristic of this process. Our findings challenge the common previous expectations concerning key characteristics of the transformation from the liquid to the glassy state, because it sug...
An accurate, an efficient, sensitive, stability indicting RP-HPLC method has designed and developed authenticated for the instantaneous determination of Emtricitabine, Dolutegravir Tenofovir by pharmaceutical dosage method. The retention time Emtricitabine (ECT) (DTG) (TEN) 2.088, 2.491 2.919 minutes respectively compared with standard drugs time.
Terapi HIV/AIDS terus mengalami perkembangan. Rejimen ARV terbaru saat ini menggunakan dolutegravir dalam rejimen KDT-ARV berupa KDT-TLD, yang berisi 2NRTI + INSTI. baru diteliti mampu menekan jumlah virus lebih cepat, mengurangi efek neuropsikiatri, dan resistensi pada sebelumnya efavirenz. Inisiasi juga disarankan sedini mungkin (jika belum ada infeksi oportunistik), agar dapat meningkatkan h...
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