More than 350 inherited diseases have been reported in dogs and at least 50% of them have human counterparts. To remove the diseases from dog breeds and to identify canine models for human diseases, it is necessary to find the mutations underlying them. To this end, two methods have been used: the functional candidate gene approach and linkage analysis. Here we present an evaluation of these in...

In recent years Canis familiaris, the domestic dog, has drawn considerable attention as a system in which to investigate the genetics of disease susceptibility, morphology and behavior. Because dogs show remarkable intrabreed homogeneity, coupled with striking interbreed heterogeneity, the dog offers unique opportunities to understand the genetic underpinnings of natural variation in mammals, a...

PURPOSE As pet ownership increases, sensitization to animal allergens due to domestic exposure is a concern. Sensitization to animal allergens may occur from indirect exposure, as well as direct ownership of animals. However, there have been conflicting results regarding the association between pet ownership and sensitization to animal allergens in adults. METHODS In total, 401 patients with ...

World-wide concern over emerging vector-borne diseases has increased in recent years for both animal and human health. In the United Sates, concern about vector-borne diseases in canines has focused on Lyme disease, anaplasmosis, ehrlichiosis, and heartworm which infect domestic and wild canids. Of these diseases, Lyme and anaplasmosis are also frequently diagnosed in humans. Gray wolves (Canis...

Prion diseases are invariably fatal and highly infectious neurodegenerative diseases affecting humans and animals. The neurodegenerative diseases such as Creutzfeldt-Jakob disease, variant Creutzfeldt-Jakob diseases, Gerstmann-Sträussler-Scheinker syndrome, Fatal Familial Insomnia, Kuru in humans, scrapie in sheep, bovine spongiform encephalopathy (or ‘mad-cow’ disease) and chronic wasting dise...

The ultrasonographic changes recorded in urinary bladder diseases recognize a high degree of specificity in accordance with the type and degree of the medical condition. Dogs with clinical signs of pollakiuria, dysuria-stranguria, hematuria, urinary incontinence, and polydipsia and polyuria were selected for investigation. In the present study twenty-two dogs were selected having urinary bladde...

In order to reproduce and complete life cycles, ticks have feed on different hosts, thus participating as vectors reservoirs in the maintenance circulation of pathogens. Since dogs can serve suitable hosts for numerous tick species, aims this study were determine species their seasonal occurrence pet compare accuracy three indices frequently used calculate engorged female physiological age. Tic...

The recorded history of rabies goes back to 2300 BC, when a dog owner in ancient Babylon was charged for a death caused by a dog bite. Ancient Greek philosophers such as Democritus, Aristotle and Celsus as well as the prominent physician Galen, had warned people of the dangers associated with the bite of a mad dog, showing that the infectivity of the animal was suspected some 2000 years ago. Ho...