We calculate the two-, threeand (for the first time) four-point correlation functions of the COBE -DMR 4-year sky maps, and search for evidence of non-Gaussianity by comparing the data to Monte Carlo-simulations of the functions. The analysis is performed for the 53 and 90 GHz channels, and five linear combinations thereof. For each map, we simulate an ensemble of 10 000 Gaussian realisations b...

Data from the literature indicate that genomic imprint marks are disturbed in human pluripotent stem cells (PSCs). GNAS is an imprinted locus that produces one biallelic (Gsα) and four monoallelic (NESP55, GNAS-AS1, XLsα, and A/B) transcripts due to differential methylation of their promoters (DMR). To document imprinting at the GNAS locus in PSCs, we studied GNAS locus DMR methylation and tran...

The buried hetero-structure (BH) InGaAsP-InP waveguide is used for asystem of double microring resonators (DMR). The light transmission and location ofresonant peaks are determined for six different sets of ring radii with different ordermode numbers. The effect of changing middle coupling coefficient on the box likeresponse is studied. It is found that the surge of coupling coefficient to the ...

Abstract Funding Acknowledgements Type of funding sources: None. Background The uncoupling right ventricular (RV) function to pulmonary circulation (Pc) represents a prognostic index in patients affected by degenerative mitral regurgitation (DMR) undergoing surgical or percutaneous repair. In this context, the deterioration Left Atrial (LA) dynamics favors development venous congestion and vasc...

Several lines of evidence indicate that plant-derived antioxidant compounds can be used as anticancer agents to support conventional pharmacological therapy. In this context, heme-oxygenase-1 (HO-1) modulation has been proven represent a valid approach for reducing cancer cells’ proliferation through the activation apoptosis and ferroptosis. This study focused on three little studied HO-1 induc...

We present an application of the fast Independent Component Analysis FastICA method to the COBE-DMR 4yr data. Although the signal-to-noise ratio in the COBE-DMR data is typically ∼ 1, the approach is able to extract the CMB signal with high confidence when working at high galactic latitudes. However, the foreground emission components have too low a S/N ratio to be reconstructed by this method ...

A60-year-old man was referred to our intervention laboratory for direct myocardial revascularization (DMR). He had received maximal medical therapy and had undergone coronary bypass surgery 10 years earlier, and his peripheral coronary anatomy was now found to be unsuited for surgical revascularization. In addition, the lesions on coronary angiography proved to be unfit for percutaneous revascu...

BACKGROUND Data from epidemiological and animal model studies suggest that nutrition during pregnancy may affect the health status of subsequent generations. These transgenerational effects are now being explained by disruptions at the level of the epigenetic machinery. Besides in vitro environmental exposures, the possible impact on the reprogramming of methylation profiles at imprinted genes ...

We review our recent claim that there is evidence of non-Gaussianity in the 4 Year COBE DMR data. We present some new results concerning the effect of the galactic cut upon the non-Gaussian signal. These findings imply a localization of the non-Gaussian signal on the Northern galactic hemisphere. I EVIDENCE FOR CMB NON-GAUSSIANITY In a recent paper [1] we showed that the 4 Year COBE DMR data ex...