OBJECTIVE AND METHODS This health technology assessment (HTA) report synthesises systematically randomized controlled studies (RCT) on the therapy of moderate and severe psoriasis vulgaris which were published between 1999 and 2004; it includes some important clinical studies which have been published after 2004 and thus updates the English HTA report by Griffiths et al. [1]. The major objectiv...

The treatment of psoriasis vulgaris in the first half of the 20th century revolved on the intake of arsenical preparations and undecylenic acid and the topical use of mainly keratolytics, chrysarobin, tar regimens, and dithranol formulations. In 1951 a major event leading to a dramatic change occurred when a 36-year-old man known only by the initials L.R. had a remission at New York’s Kings Cou...

Several topical treatments such as ointments, keratolytics, dithranol, tar, corticosteroids and Vitamin D3 analogues are commonly used in the treatment of mild and/or moderate psoriasis. These treatments can be associated with a variety of local and systemic side effects, as well as to very often unsatisfactory results. The purpose of this critical review of the literature is to evaluate the ef...

3 Rivlin RS, Young EA, eds. Symposium on evidence relating selected vitamins and minerals to health and disease in the elderly population in the United States.competence of the elderly. Effect of short term nutritional supplementation on cell-mediated immunity and lymphocyte subsets. Fast atrial fibrillation induced by treatment of psoriasis with azathioprine We describe a patient with psoriasi...

Ein 41-jähriger Patient stellte sich notfallmäßig mit disseminierten, juckenden Plaques vor, welche 8 Wochen zuvor am Capillitium begonnen und im Verlauf auf das gesamte Integument ausgebreitet hätten. Bei Verdacht eine Psoriasis vulgaris war Behandlung Calcipotriol/Betamethason-Schaum erfolgt, was jedoch nur einen kurzfristigen therapeutischen Effekt erzielt hätte, ebenso wie die Einnahme von ...

A 63-year-old Kenyan Asian man began haemodialysis involvement, the risk of secondary infection leading to either line sepsis or peritonitis, and the difficulties in in April 1997. He initially presented in 1988 dialysis dependent with an ANCA-associated systemic vasculperforming surgical procedures through involved skin. Koebner’s phenomenon (the recurrence of skin lesions itis, and was treate...