OBJECTIVE Our aim was to describe the patient characteristics, clinical-epidemiological profile, and treatment outcome of childhood tuberculosis (TB). METHODS A retrospective, descriptive study was undertaken of 1212 children aged 0 to 18 years admitted to Beijing Children's Hospital for the treatment of TB from January 2002 to December 2010. Statistical significance of category variables was...

Tuberculosis (TB) screening in pregnancy using tuberculin skin test (TST) is recommended in case of symptoms of TB disease, close contact with a patient with infectious TB, or high risk of developing active disease. The new interferon gamma release assay (IGRA) tests are recommended in BCG-vaccinated pregnant women with positive TST and no known risk factors for TB, and in those immunocompromis...

UNLABELLED Tuberculosis (TB)/HIV co-infection significantly changes the natural history of both diseases. Proper comprehension and clinical management of co-infected TB/HIV patients is still a challenge, particularly in places like Brazil, where both types of infection are prevalent. OBJECTIVES Evaluate the frequency of the clinical forms of TB in HIV-infected patients; correlate the clinical...

a twelve-year-old girl with disseminated tuberculosis was complicated by psychogenic vomiting and multiple drugs’ adverse effects. she was admitted to our hospital, complaining of fever, cough and abdominal pain. diagnosis of tb was obtained by abdominal ct-scan and open liver biopsy. during the anti-tb treatment, hepatitis, hemolytic anemia and pancreatitis occurred due to some drugs' side eff...

BACKGROUND Leucocyte activating chemokines such as CCL2, CCL3, and CXCL8 together with proinflammatory IFNgamma, TNFalpha and downmodulatory IL10 play a central role in the restriction of M. tuberculosis infections, but is unclear whether these markers are indicative of tuberculosis disease severity. METHODOLOGY We investigated live M. tuberculosis- and M. bovis BCG-induced peripheral blood m...

BACKGROUND Tuberculosis (TB) screening in migrant children, including immigrants, refugees and asylum seekers, is an ongoing challenge in low TB incidence countries. Many children from high TB incidence countries harbor latent TB infection (LTBI), and some have active TB disease at the point of immigration into host nations. Young children who harbor LTBI have a high risk of progression to TB d...

TOPIC: Chest Infections TYPE: Medical Student/Resident Case Reports INTRODUCTION: Cerebral tuberculomas is a rare form of extrapulmonary tuberculosis (TB). Due to lack tests available for confirmatory diagnosis, the diagnosis difficult. However, missing could lead catastrophic consequences. Here, we report case disseminated presented with multiple ring enhancing lesions in brain. CASE PRESENTAT...

Pediatric tuberculosis (TB) is different than that in adults in several ways. (1) The diagnosis of TB is more difficult in children due to non-specific or complete absence of symptoms and difficulty in confirming the diagnosis microbiologically. (2) Young children suffer more extrapulmonary and disseminated TB than adults. (3) Treatment of TB in children is challenging due to the lack of pediat...