نتایج جستجو برای: disruption risk
تعداد نتایج: 999940 فیلتر نتایج به سال:
BACKGROUND Sleep deficiency is a major public health problem. There are limited human data on whether sleep duration or disruption are risk factors for prostate cancer. METHODS We prospectively followed 32,141 men in the Health Professionals Follow-Up Study who reported their typical sleep duration in 1987, 2000, and 2008. We identified 4,261 incident prostate cancer cases, including 563 leth...
PURPOSE Shift work, short sleep duration, employment as a flight attendant, and exposure to light at night, all potential causes of circadian disruption, have been inconsistently associated with breast cancer (BrCA) risk. The aim of this meta-analysis is to quantitatively evaluate the combined and independent effects of exposure to different sources of circadian disruption on BrCA risk in women...
This paper considers a newsvendor model for single product to focus on the importance of coordination under demand and supply uncertainties where raw materials are procured from two unreliable suppliers without any emergency resource; main supplier (which is cheaper but more unreliable) prone random disruption and, therefore, it can satisfy all or nothing buyer’s order, while backup expensive l...
BACKGROUND AND PURPOSE Surface disruption, either ulceration or fibrous cap rupture, has been identified as a key feature of the unstable atherosclerotic plaque. In this prospective observational study, we sought to determine the characteristics of the carotid lesion that predict the development of new surface disruption. MATERIALS AND METHODS One hundred eight asymptomatic individuals with 5...
This paper focuses on the importance of decoupling recurrent supply risk and disruption risk when planning appropriate mitigation strategies. We show that bundling the two uncertainties leads a manager to underutilize a reliable source while over utilizing a cheaper but less reliable supplier. As in Dada, Petruzzi and Schwarz [6], we show that increasing quantity from a cheaper but less reliabl...
We investigated whether karyotype analysis and mutational screening by next generation sequencing could predict outcome in 101 newly diagnosed chronic lymphocytic leukemia patients with high-risk features, as defined by the presence of unmutated IGHV gene and/or 11q22/17p13 deletion by FISH and/or TP53 mutations. Cytogenetic analysis showed favorable findings (normal karyotype and isolated 13q1...
Multiparty cryptography is an important topic in contemporary cryptography. In this paper we examine the security of some multi-party signature schemes. In particular, we point out that a multisignature scheme is vulnerable to universal forgery by an insider attacker under reasonable assumptions. This attack can be applied to some generalizations as well. Then we present a universal forgery att...
W study sourcing in a supply chain with three levels: a manufacturer, tier 1 suppliers, and tier 2 suppliers prone to disruption from, e.g., natural disasters such as earthquakes or floods. The manufacturer may not directly dictate which tier 2 suppliers are used but may influence the sourcing decisions of tier 1 suppliers via contract parameters. The manufacturer’s optimal strategy depends cri...
Background & Objectives: To determine the risk factors for acute diarrhea disease in children. Methods: This study involved 220 cases and 220 controls in Dr. Sheykh Hospital, a specialzed pediatric hospital in Mashhad. Cases were children seen in the emergency department with loose watery feces, diagnosed as acute diarrhea by the physician. The controls were selected from the same setting as th...
This article develops a model and analysis to provide insight into two effective remedies to increase supply chain resilience: (i) contracting with a secondary flexible backup supplier; and (ii) monitoring primary suppliers to obtain disruption risk information. To investigate the true value of these strategies, an analysis is performed under imperfect information concerning the disruption risk...
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