in classical mechanics, considering hook’s law stress is a linear function of strain. while in strain gradient theory stress is a function of strain and strain differentials. in this paper, novel formulation relating stress and strain and also new boundary conditions are derived based on minimum potential energy principle. in strain gradient theory a length coefficient parameter is defined. thi...

In the present study, molecular dynamics simulations have been utilized to provide fundamental understanding of melting behavior of pure Pd and Pt nanoparticles with the size of 10 nm in diameter, both free and graphene-supported during continuous heating. The embedded atom method is employed to model the metal-metal interactions, whereas a Lennard-Jones potential is applied to describe the met...

Ultrasound elastography has been widely applied in clinical diagnosis. To produce high-quality elastograms, displacement estimation is important to generate ne displacement map from the original ratio-frequency signals. Traditional displacement estimation methods are based on the local information of signals pair, such as cross-correlation method, phase zero estimation. However, the tissue move...

In this paper, a plane quadrilateral element with rotational degrees of freedom is developed. Present formulation is based on a hybrid functional with independent boundary displacement and internal optimum strain field. All the optimality constraints, including being rotational invariant, omitting the parasitic shear error and satisfying Fliepa’s pure bending test, are considered. Moreover, the...

Accurate functional measurement in cardiovascular diseases is important as inaccuracy may compromise diagnostic decisions. Cardiac function can be assessed using displacement encoding with stimulated echoes, resulting in three signal components. The free induction decay (FID), arising from spins undergoing T(1) -relaxation, is not displacement encoded and impairs the displacement acquired. Tech...

Using a minicircle DNA primer-template, the wild-type catalytic subunit of herpes simplex virus type 1 (HSV-1) DNA polymerase (pol) was shown to lack significant strand displacement activity with or without its processivity factor, UL42. However, an exonuclease-deficient (exo ) pol (D368A) was capable of slow strand displacement. Although UL42 increased the rate (2/s) and processivity of strand...

In this paper we define a generic decision problem — the displacement problem. The displacement problem arises when we have to make a sequence of decisions and each new decision that must be made has an explicit link back to the previous decision that was made. This link is quantified by means of the displacement function. One situation where the displacement problem arises is that of dynamical...

Using a minicircle DNA primer-template, the wild-type catalytic subunit of herpes simplex virus type 1 (HSV-1) DNA polymerase (pol) was shown to lack significant strand displacement activity with or without its processivity factor, UL42. However, an exonuclease-deficient (exo(-)) pol (D368A) was capable of slow strand displacement. Although UL42 increased the rate (2/s) and processivity of stra...

BACKGROUND Quantitative blood flow and aspects of regional myocardial function such as myocardial displacement and strain can be measured using phase-contrast cardiovascular magnetic resonance (PC-CMR). Since a gadolinium-based contrast agent is often used to measure myocardial infarct size, we sought to determine whether the contrast agent affects measurements of aortic flow and myocardial dis...