نتایج جستجو برای: disorders glucose transporter type 4 lipid metabolism disorders 3
تعداد نتایج: 4266259 فیلتر نتایج به سال:
OBJECTIVE Fibroblast growth factor 21 (FGF21) has emerged as an important metabolic regulator of glucose and lipid metabolism. The aims of the current study are to evaluate the role of FGF21 in energy metabolism and to provide mechanistic insights into its glucose and lipid-lowering effects in a high-fat diet-induced obesity (DIO) model. RESEARCH DESIGN AND METHODS DIO or normal lean mice wer...
Stimulated CD4(+) T lymphocytes can differentiate into effector T cell (Teff) or inducible regulatory T cell (Treg) subsets with specific immunological roles. We show that Teff and Treg require distinct metabolic programs to support these functions. Th1, Th2, and Th17 cells expressed high surface levels of the glucose transporter Glut1 and were highly glycolytic. Treg, in contrast, expressed lo...
Background: Obesity is one of the known risk factors of diabetes. Nowadays in parallel with industrialization of societies, changes in lifestyle and diet habits and also decreased physical activity, the prevalence of obesity is increasing. The objective of this study is to evaluate the effect of change in body weight on blood glucose disorders rate after 3 years of Tehran lipid and glucose stud...
Changes in the intestinal microbiome have been associated with obesity and type 2 diabetes, epidemiological studies of effects fecal transfer germ-free mice. We review mechanisms by which alterations contribute to development metabolic diseases, recent advances, such as on lipid metabolism. Strategies developed modify reverse alterations, might be used therapies. discuss approaches that shown m...
The Russian Society of Cardiology (RKO) With the participation of: National for Study Atherosclerosis (NOA), Association Endocrinologists (RAE), Cardiosomatic Rehabilitation and Secondary Prevention (RosOKR), Scientific Medical Therapists (RNMOT), Eurasian Cardiologists, (EAT), Gerontologists Geriatricians
The physiology and the pathology of Central Nervous System (CNS) is very complex, only by understanding it scientific research might develop effective treatments. Neurocognitive Disorders, extremely diffused diseases, have a multifactorial aetiology, in which lipid homeostasis plays an important role, as known. aim this mini-review focus on interesting recently published researches topic, order...
Peroxisome proliferator-activated receptors (PPARs) are implicated in several metabolic disorders with altered glucose and lipid metabolism, including atherosclerosis and diabetes. In the present study, we evaluated the in vitro and ex vivo effects of high glucose concentrations on macrophage PPAR mRNA expression. Exposition of monocyte-derived macrophages isolated from healthy donors to a high...
Part 1: The metabolism of cancer cells -- Chapter Glucose Metabolism 2: Glutamine 3: Amino Acid 4: Lipid 5: Epigenetics and oncometabolites Heterogeneity Cancer - Specific oncogenetic mutations lead to specific metabolic phenotypes within the same tissue origin Intratumoral heterogeneity cell Differential in vitro vivo Carcinoma associated fibroblasts Characteristics CAF's Reverse Warbug EFF Me...
Diabetes mellitus (DM) is one of the most prevalent metabolic disorders in world and characterized by excessive blood glucose levels, which lead to deranged carbohydrate, protein, lipid metabolisms. At its core, DM an impairment insulin metabolism, leading a plethora clinical features. The thyroid gland another vital cog wheel endocrine system, hormones synthesized it are heavily involved contr...
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