Target audience: Researchers in the field of diffusion weighted magnetic resonance imaging interested in new tractography methods. Purpose: This work develops a tractography algorithm to leverage fibre dispersion estimates derived from fitting parametric models of orientation dispersion to diffusion data. Tractography techniques are powerful tools to probe white matter (WM) connectivity non-inv...

The purpose of this work is to obtain the voxelization of a series of tomography slices in order to provide a voxelized human phantom throughout a MatLab algorithm, and the consequent simulation of the irradiation of such phantom with the photon beam generated in a Theratron 780® (MDS Nordion) 60 Co radiotherapy unit, using the Monte Carlo transport code MCNP (Monte Carlo N-Particle), version 5...

Purpose: To develop and test an integrated simulation system based on the digital Extended Cardio Torso (XCAT) phantom for 4-dimensional (4D) radiation therapy of lung cancer. Methods: A computer program was developed to facilitate the characterization and implementation of the XCAT phantom for 4D radiation therapy applications. To verify that patient-specific motion trajectories are reproducib...

White matter structures composed of myelinated axons in the living human brain are primarily studied by diffusion-weighted MRI (dMRI). These long-range projections are typically characterized in a two-step process: dMRI signal is used to estimate the orientation of axon segments within each voxel, then these local orientations are linked together to estimate the spatial extent of putative white...

PURPOSE In longitudinal oncological and brain PET/CT studies, it is important to understand the repeatability of quantitative PET metrics in order to assess change in tracer uptake. The present studies were performed in order to assess precision as function of PET/CT system, reconstruction protocol, analysis method, scan duration (or image noise), and repositioning in the field of view. METHO...

background: cone-beam computed tomography (cbct) is a new imaging technology that has been widely used in implantology, oral and maxillofacial surgery and orthodontics. this method provides 3-d images that are composed of voxel, which is the smallest image unit, and determines image resolution. smaller voxel is associated with the higher resolution and also greater radiation exposure. this stud...

This paper presents a fast image synthesis procedure for elastic volumes under deformation. Given the node displacements of a mesh and the 3D image voxel data of an undeformed volume, the method maps the image plane pixels to be synthesized from the deformed configuration back to the nominal pre-deformed configuration, where the pixel intensities are obtained easily through interpolation in the...

The equivalent dose rate per positron fluence for the human eye lens is calculated using a Monte Carlo simulation code, EGS5, with two mathematical models (a computational head voxel phantom and a simple eye model). The eye lens doses for medical staff and carers as received from a radiopharmaceutical such as F-FDG, which is used in PET examinations, when spilled on the floor, and from positron...

background: high-energy linear accelerator (linac) is a valuable tool and the most commonly device for external beam radiation treatments in cancer patients. in the linac head, high-energy photons with energies above the threshold of interaction produce photoneutrons. these photoneutrons deliver the extra dose to the patients in the planning treatment and increase the risk of secondary cancer. ...

Log file-based methods are attracting increasing interest owing to their ability to validate volumetric-modulated arc therapy outputs with high resolution in the leaf and gantry positions and in delivered dose. Cross-validation of these methods for comparison with measurement-based methods using the ionization chamber/ArcCHECK-3DVH software (version 3.2.0) under the same conditions of treatment...