The anodic polarographic behaviour of josamycin (a macrolide antibiotic) has been studied using direct current (DC(t)) polarography and differential pulse polarography (DPP). In Britton-Robinson buffers (BRb) josamycin exhibited well-defined anodic polarographic waves in the pH range 2-8. In BRb of pH 6, the diffusion-current constant was 1.62 microA mmol(-1) (n = 6). The current-concentration ...

Techniques have been developed for detection, quantitation, and isolation of bacterial metallothioneins (MTs) from cyanobacterial species. These methods involve differential pulse polarography and reverse-phase high-performance liquid chromatography (HPLC) and have allowed detection of picomole quantities of these high sulfhydryl content proteins. The prokaryotic molecule was found to be induce...

The electrochemical behaviour of tobacco mosaic virus (TMV) and its isolated protein was studied using differential pulse (DP) voltammetry at a graphite electrode and by direct current (DC) polarography in Brdicka solution. TMV and its isolated protein were found to be electrooxidized at the graphite electrode in the adsorbed state. Both species yielded two oxidation peaks on DP voltammograms. ...

The voltammetric behaviour of cyproterone acetate (CPA) was studied using direct current (DCt) and differential pulse polarography (DPP). The drug manifests cathodic waves over the pH range of 4-11.8. In Britton-Robinson buffer (BRb) of pH 10, the diffusion current-concentration relationship was found to be rectilinear over the range 3.2-32 μg/mL and 0.5-14 μg/mL using DCt and DPP modes, respec...

Two new ligands, ammonium 2,6-dimethyl morpholine dithiocarbamate (ADMMDTC) and ammonium 3-methyl piperdine dithiocarbamate (AMP-DTC) were synthesized in the laboratory. The method was based on chelation of manganese(II) with ADMM-DTC/AMP-DTC in the presence of NH4OH at pH 6.2 and 6.8 to produce catalytic hydrogen currents at -0.72 V and -0.62 V vs. SCE respectively and prior detected by D.C po...