نتایج جستجو برای: differential co

تعداد نتایج: 611330  

2014
Chuan Gao Shiwen Zhao Ian C. McDowell Christopher D. Brown Barbara E. Engelhardt

Identifying latent structure in large data matrices is essential for exploring biological processes. Here, we consider recovering gene co-expression networks from gene expression data, where each network encodes relationships between genes that are locally co-regulated by shared biological mechanisms. To do this, we develop a Bayesian statistical model for biclustering to infer subsets of co-re...

2012
Qiang Huang Thomas White Guanbo Jia Mirco Musolesi Nil Turan Ke Tang Shan He John K. Heath Xin Yao

In many scientific fields, from biology to sociology, community detection in complex networks has become increasingly important. This paper, for the first time, introduces Cooperative Co-evolution framework for detecting communities in complex networks. A Bias Grouping scheme is proposed to dynamically decompose a complex network into smaller subnetworks to handle large-scale networks. We adopt...

2012
Walter Berghoff

In Lyme disease concurrent infections frequently occur. The clinical and pathological impact of co-infections was first recognized in the 1990th, i.e. approximately ten years after the discovery of Lyme disease. Their pathological synergism can exacerbate Lyme disease or induce similar disease manifestations. Co-infecting agents can be transmitted together with Borrelia burgdorferi by tick bite...

2012
Cord F. Stäehler Andreas Keller Petra Leidinger Christina Backes Anoop Chandran Jöerg Wischhusen Benjamin Meder Eckart Meese

Co-regulation of genes has been extensively analyzed, however, rather limited knowledge is available on co-regulations within the miRNome. We investigated differential co-expression of microRNAs (miRNAs) based on miRNome profiles of whole blood from 540 individuals. These include patients suffering from different cancer and non-cancer diseases, and unaffected controls. Using hierarchical cluste...

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