The objective of this study was to investigate the effects of the combined RF radiation (837 MHz CDMA plus 1950 MHz WCDMA) signal on levels of intracellular reactive oxygen species (ROS) in neuronal cells. Exposure of the combined RF signal was conducted at specific absorption rate values of 2 W/kg of CDMA plus 2 W/kg of WCDMA for 2 h. Co-exposure to combined RF radiation with either H2O2 or me...

The results of a study (Zuckner, 1961) evaluating the therapeutic response of intra-articularly administered triamcinolone acetonide* (hereafter referred to as TActn) and triamcinolone diacetate* (TDac) suggested that large doses of these hormones had a profound systemic effect. The injection of either of these hormones in a dose of 100 mg. into a knee joint affected by rheumatoid arthritis res...

This report examines the use of 5-(and-6)-carboxyfluorescein diacetate succinimidyl ester (CFSE) to determine the site, duration and cell type responsible for antigen presentation in vivo. Evidence that CFSE-labelled T cells can be used to determine where various types of antigens are presented, including auto-antigens, oral antigens and cell-associated foreign antigens, is provided. Using this...

The reaction of 1-(p-hydroxyaryl)cyclobutanols and phenyl iodide(III) diacetate in hexafluoroisopropanol and water produced spiro cyclohexadienone lactones via a domino reaction.

Dithranol was introduced into anti-psoriatic therapy in 1916, but the principle of its activity remains unkown with regard to the quantitative aspects of its efficacy e.g. in enzyme inhibition, D N A interaction and interference with lipid metabolism. In vitro experiments have indicated that dithranol irreversibly inhibits glucose-6-phosphate-dehydrogenase (EC 1.1.1.49) [10] and the incorporati...

OBJECTIVES Reduction in faecal shedding of Shiga toxin-producing enterohaemorrhagic Escherichia coli (EHEC) in food-producing animals is a viable strategy to minimize human disease initiated by exposure to these microorganisms. To this end, an intervention strategy involving the electrostatic hybridization of two commonly used anti-infective agents for veterinary practice (i.e. chlorhexidine an...

Fluorescein-based sensors are the most widely applied class of zinc probes but display adventitious localization in live cells. We present here a peptide-based localization strategy that affords precision in targeting of fluorescein-based zinc sensors. By appending the zinc-selective, reaction-based probe Zinpyr-1 diacetate (DA-ZP1) to the N-terminus of two different targeting peptides we achie...