background and objective: alleviation of serum glucose level and lipid profile in diabetic patients using herbal medications is of great importance. in the present study, the effect of oral consumption of olive leaves on serum glucose level and lipid profile was investigated. materials and methods: male wistar rats were divided into four groups including control, control under treatment, diabet...

diabetes is a metabolic disorder which affects whole body systems including reproductive system. diabetes is also a contributing factor to infertility. metformin is one of the most common drugs to control hyperglycemia. in this study, 36 adult sprague-dawley female rats (170-210 g) were divided into 3 groups (control, diabetic and diabetic-treated by metformin). in second and third groups, diab...

background: saffron is the dried stigmata of the flowers of saffron (crocus sativus l., iridaceae). saffron is well known for the treatment of gastric disorders in traditional medicine.   objectives: in the search for new potential antiulcer agents, the effects of the ethanol extract of saffron and its active constituents crocin and safranal as compared with omeprazole against gastric ulcer ind...

introduction: repeated hyperglycemia play an important role in the development of atherosclerosis in diabetic patients. endothelium is the organ of the first-line defense against atherosclerosis and nitric oxide has a major role in this task. the aim of this study was to determine changes in plasma nitric oxide metabolites concentration during glucose tolerance test in type 2 diabetic rats. met...

BACKGROUND: Diabetes mellitus is a chronic metabolic disorder, affected by fructose, and artificial sweeteners. Aspartame fructose are popularly used, diabetics, as substitutes to glucose. AIM: This study evaluated the effect of high aspartame on vascular reactivity, glucose, hepatic metabolism in diabetic rats. MATERIALS AND METHODS: Forty-eight male rats were divided into six groups: Control,...

abstract          background and objective: according to iranian, asian, indian, and chinese traditional medicine, basil is used in the treatment of different diseases. in this study, the effect of basil on lowering the blood glucose was examined in healthy and diabetic rats.         methods: sixty wistar rats were divided into a control group(n=10), a basil receiving group (n=20) and a diabeti...

objective(s):the present study investigated the antidiabetic and hypolipidemic properties of dorema aucheri leave hydroalcoholic extract in nicotinamide-streptozotocin induced type 2 diabetic rats. materials and methods: nicotinamide/streptozotocin-induced diabetic rats were supplemented orally with three different doses of d.  aucheri (100, 200 and 400 mg/kg bw) or glibenclamide (0.25 mg/kg) f...

objectives the aim of this study was to examine the effect of flaxseed on gene expression of intestinal transporters: niemann-pick c1 like 1 (npc1l1), atp-cassette binding proteins g5 (abcg5) and g8 (abcg8). methods animals were randomly divided into 3 groups 8 rats in each group: group1; normal diet, group2; diabetic rats, and group3; diabetic rats + 4% (w/w) flaxseed. after one-month rats wer...

Background: This study aimed to investigate the possible apoptotic role of bortezomib (BMZ) on pancreatic islets streptozotocin (STZ)-induced diabetic rats.

Effects of magnetic hydroethanolic extract Nigella sativa and magnesium oxide nanoparticles (MgO) on catalase gene expression in liver diabetic male rats