X Matti D. Allen, Timothy J. Doherty, Charles L. Rice, and Kurt Kimpinski School of Medicine, Queen’s University, Kingston, Ontario, Canada; School of Kinesiology and Health Studies, Faculty of Health Sciences, Queen’s University, Kingston, Ontario, Canada; School of Kinesiology, Faculty of Health Sciences, University of Western Ontario, London, Ontario, Canada; Department of Clinical Neurologi...

AIMS To examine the relations between work characteristics as defined by the Job Demand-Control-Support model (JDCS) (that is, job demands, decision latitude, and social support), diabetes related burden (symptoms, seriousness of disease, self care activities, and disease duration), and fatigue in employees with diabetes mellitus. METHODS Employees (n = 292) aged 30-60 years, with insulin tre...

An abnormal and transient increase of the Coulter mean red cell volume (MCV) was observed in four of 10 patients with diabetic decompensation. A sequential study of haematological and biochemical measurements in these patients revealed that this phenomenon was associated with the hyperosmolar state. The proposed mechanism and the clinical implications of this change are briefly discussed.

BACKGROUND Diabetic neuropathy and idiopathic neuropathy are among the most prevalent neuropathies in human patients. The molecular mechanism underlying pathological changes observed in the affected nerve remains unclear but one candidate molecule, the receptor for advanced glycation end-products (RAGE), has recently gained attention as a potential contributor to neuropathy. Our previous studie...

Diabetic Peripheral Neuropathies (DPN) are chronic debilitating complications following Diabetes mellitus. DPN refers to signs and symptoms of peripheral nerve dysfunction in a patient with mellitus (DM) whom other causes neuropathies have been excluded. The incidence neuropathy is strongly associated microvascular comorbidities. In Ayurveda, Prameha one Ashtamahagada, which will finally transf...

OBJECTIVE The goal of this study was to determine whether surrogate markers based primarily on changes in the size of a wound can be used to correctly predict which individuals with diabetic neuropathic foot ulcers will heal after 12 or 20 weeks of care. RESEARCH DESIGN AND METHODS This is a retrospective cohort study using the Curative Health Services database. As many as 39,918 neuropathic ...