In a prospective study of idiopathic glomerulonephritis we determined the natural history of 49 adult patients (12 primary IgA nephropathy, 13 thin GBM nephropathy, 20 normal renal tissue and 4 miscellaneous nephropathies) who presented with idiopathic non-proteinuric non-azotemic hematuria of at least six months duration, in the absence of hypertension and with a negative urological work-up. T...

BACKGROUND Diabetic nephropathy or diabetes-related nephropathies represents one of the most relevant causes of renal failure in recent years. This complex pathological picture becomes particularly severe as time elapses and after starting renal replacement therapy (RRT). METHODS In an attempt to investigate the evolution of the major clinical features, a retrospective study was carried out o...

In patients with HIV, the use of highly active antiretroviral therapy has improved life expectancy. At the same time, this increase in life expectancy has been associated with a higher frequency of chronic kidney disease due to factors other than HIV infection. Besides HIV-associated nephropathy, a number of different types of immune complex and non-immune complex-mediated processes have been i...

Progressive renal disease is associated with the development of fibrosing lesions in the glomerulusglomerulosclerosis, and in the interstitiuminterstitial fibrosis. The mechanisms involved in this processes are shared by the inflammatory cells and the resident cells: glomerular mesangial cell, interstitial fibroblast, tubular epithelial cell and vascular smooth muscle cell. These resident cells...

The authors present the results of follow-up observations children that had undergone neonatal nephropathy. A observation revealed newborns from mothers with chronic kidney diseases are at risk for development nephropathies. long-term positive examination who underwent nephropathy and received a course anti-relapse treatment proved effectiveness renal protection.

OBJECTIVE To evaluate whether the protein:creatinine ratio in spot morning urine samples is a reliable indicator of 24 hour urinary protein excretion and predicts the rate of decline of glomerular filtration rate and progression to end stage renal failure in non-diabetic patients with chronic nephropathy. DESIGN Cross sectional correlation between the ratio and urinary protein excretion rate....