In subjects with type 2 diabetes, both defects of insulin secretion and insulin resistance contribute to the development of hyperglycaemia. The major goals of treatment are to optimise blood glucose control, and normalise the associated lipid disturbances and elevated blood pressure. Pharmacologic treatment is often necessary. This paper discusses new forms of oral treatment for subjects with t...

Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disorder, which affects more than 300 million people globally. The common effect of uncontrolled diabetes is the state of hyperglycemia, which results from beta-cell dysfunction as well as insulin resistance, which is accompanied with microvascular and macrovascular complications. As hyperglycemia defines diabetes, glycemic control is fun...

New treatments for diabetes are always exciting in the beginning but as experience grows their position in management becomes less certain. This review focuses on DPP4 inhibitors and their place in management of type 2 diabetes. Although hypoglycaemia is rarely an issue, the effectiveness in reduction in blood sugar is greatest at the higher blood sugar levels, hence much of the value of using ...

Diabetes and psychiatric disorders have a bidirectional relationship in which they mutually influence each other numerous ways. mental health issues reciprocal condition influences the unique manner. In addition, presence of concurrent disorder, such as depression, may hinder management diabetes by reducing medication adherence. Blood glucose testing insulin injection are only two examples how ...

La diabetes mellitus (DM) es una enfermedad metabólica crónica con alta prevalencia en nuestro medio: se estima que aproximadamente el 13,8% de la población tiene antecedentes de DM y un 6% de estos no han sido todavía diagnosticados1. Es sabido que el 25% de los pacientes que ingresan en un centro hospitalario tienen antecedentes de DM y entre un 30-40% de los atendidos en los servicios de Urg...

OBJECTIVE To investigate the effectiveness of different treatments for gestational diabetes mellitus (GDM). DESIGN Systematic review, meta-analysis and network meta-analysis. METHODS Data sources were searched up to July 2016 and included MEDLINE and Embase. Randomised trials comparing treatments for GDM (packages of care (dietary and lifestyle interventions with pharmacological treatments ...

Problem solving is an essential skill for effective diabetes self-management. Evidence suggests that problem-solving therapy (PST) approaches, used in the context of broader diabetes educational or lifestyle interventions, may be effective for mood and select diabetes outcomes. As a stand-alone treatment, formal PST adapted for diabetes self-management is a promising behavioral intervention for...

Recent decades have seen a resurgent interest in traditional plant treatments for diabetes. This has pervaded nutrition, the pharmaceutical industry and academic research, fuelled by a growing public interest and awareness of so-called complementary and natural types of medicine. Before the advent of insulin therapy in 1922, starvation diets and traditional plant treatments were the cornerstone...

Diagnosis of type 2 diabetes mellitus encompasses multiple pathophysiological and clinical situations. Type 2 diabetes mellitus is characterized by a long and changing natural history. Personal circumstances and preferences also condition the actual effectiveness and safety of drugs used. In recent decades, modern drugs have markedly expanded and improved therapeutic options. However, their eff...