AIM The purpose of this study is to see the effect of Dexketoprofen on TNF-α, IL-1, and IL-6 serum levels in Chronic Tension-Type Headache (CTTH) patients and its correlation with pain severity. METHOD The study subjects were recruited consecutively from the study population. Venous blood was taken at baseline to measure serum levels of TNF-α, IL-1, and IL-6 and after ten consecutive days of ...

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in pain whose mechanism of action is the inhibition cyclooxygenase enzymes (COXs), however, there evidence other mechanisms action, such as substance P, interaction with systems NO, monoaminergic and others. The objective present work was to study participation a-1 (prazosin) a-2 (yohimbine) adrenoceptors antagonists antinociception...

Özet Amaç: Giderek artan sayıda yapılan günübirlik bir cerrahi girişim olan laparoskopik kolesistektomide ağrı tedavisi önemli bir sorundur. Her ne kadar laparoskopik cerrahi günübirlik bir girişim olarak kabul edilse de, hastalar sıklıkla ağrı nedeniyle hospitalize edilmekte ve bu da opioid tüketimini ve opioidlerin sebep olduğu yan etkileri arttırmaktadır. Bu çalışmanın amacı, laparoskopik ko...

INTRODUCTION The aim of this study was to evaluate oral single/multiple doses of Fosfomycin Trometamol with clinical and microbiological efficacy in:Asymptomatic bacteriuria in pregnancy.Endourological procedures.Lower urinary tract infections. MATERIAL AND METHODS This prospective, uncontrolled, open label study was conducted in two tertiary hospitals over a period of three years. A total of...

BACKGROUND In this double-blind, randomized, placebo-controlled trial, the safety and analgesic efficacy of perioperative dexketoprofen were evaluated. METHODS Thirty ASA I or II patients undergoing elective hip arthroplasty were randomized to one of two groups. One group (D) received dexketoprofen 25 mg tds for 24 h before and 48 h after surgery; the second group (P) received placebo tablets...

Musculoskeletal back pain (MSBP) is one of the most common reasons for seeking medical care. A socioeconomic burden MSBP significant, as it leads to reduced working capacity adult population. It important consider that chronicity develops under impact “yellow flags”, i. e. factors contribute central sensitization (pathophysiologically) and chronicification (clinically). The factor anxiety under...