We have compared the in vitro activity of the new antifungal drug eberconazole with those of three other topical antifungal agents, clotrimazole, ketoconazole, and miconazole, against 200 strains of dermatophytes. MICs were determined by a microdilution method with optimal conditions determined in a previous study (an inoculum of 10(4) CFU/ml, an incubation temperature of 28 degrees C, an incub...

The allylamine derivative terbinafine is the first antifungal agent with primary fungicidal properties against dermatophytes which acts systemically after oral application as well as locally after topical application. Comparative oral studies carried out with griseofulvin and ketoconazole in model infections such as guinea pig trichophytosis and microsporosis revealed terbinafine to be superior...

Dermatophytes are keratinophilic fungi that infect keratinized tissues causing diseases known as dermatophytoses. Dermatophytes are classified in three genera, Epidermophyton, Microsporum, and Trichophyton. This investigation was performed to study the prevalence of dermatomycosis among 640 patients being evaluated at the dermatology clinics at Kasr elainy, El-Husein and Said Galal hospitals in...

Dematophytosis in domestic animals constitutes a constant source of infection for persons in contact with them. To have an epidemiological picture of zoophilic dermatophyte infections in Iran, a study has been carried out during a period of three years (1986-1989) in an attempt to find the causative dermatophytes which infect cats and cattle and also infected human subjects in contact with ...

Dermatophytoses belong to the most common disease entities encountered in everyday dermatological practice. Despite the fact that their clinical presentation, course and treatment response remain rather typical, they often present a considerable diagnostic and therapeutic challenge. We present a case of a 54-year-old male who presented to the outpatient clinic of the Department of Dermatology i...

Dermatophytoses form over 16–75% of all the mycological infections. It is more prevalent in tropical and subtropical countries including India, where heat and moisture play an important role. 1 Although not life threatening, its severity can cause great discomfort particularly in immunosuppressive conditions. It remains a general public health problem, which is prevalent in all age groups and b...