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Formulation of silver nitrate and silver sulphadiazine is choice of drug in topical treatment of burns and related inflammation. Ancient silver based nanomedicine of Ayurveda is raupya bhasma (RB) used in treatment of different ailments but RB is still not explored to their anti-inflammatory activity. To consider this an attempt has been made to evaluate in-vitro anti-inflammatory activity of R...
MNEI is a single chain derivative of monellin, a plant protein that can interact with the human sweet taste receptor, being therefore perceived as sweet. This unusual physiological activity makes MNEI a potential template for the design of new sugar replacers for the food and beverage industry. Unfortunately, applications of MNEI have been so far limited by its intrinsic sensitivity to some pH ...
Fragment-based lead discovery has proved to be an effective alternative to high-throughput screenings in identifying chemical matter that can be developed into robust lead compounds. The search for optimal combinations of biophysical techniques that can correctly and efficiently identify and quantify binding can be challenging due to the physicochemical properties of fragments. In order to mini...
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