نتایج جستجو برای: delta hepatitis
تعداد نتایج: 179357 فیلتر نتایج به سال:
Hepatitis delta virus (HDV) is the smallest known human and causes most severe form of viral hepatitis, yet it still not fully understood how replicates interacts with many host proteins during replication. This review aims to provide a systematic all factors currently interact HDV their mechanistic involvement in steps replication cycle. Finally, we discuss implications for therapeutic develop...
UNLABELLED Interferon alpha is the only treatment option for hepatitis delta virus (HDV). Trials investigating the efficacy of pegylated interferon alpha (PEG-IFNa) showed HDV RNA negativity rates of 25-30% 24 weeks after therapy. However, the clinical and virological long-term outcome of HDV-infected patients treated with PEG-IFNa is unknown. We performed a retrospective-prospective follow-up ...
Hepatitis delta virus (HDV) is a distant relative of plant viroids in the animal world. Similar to plant viroids, HDV replicates its circular RNA genome using a double rolling-circle mechanism. Nevertheless, the production of hepatitis delta antigen (HDAg), which is indispensible for HDV replication, is a unique feature distinct from plant viroids, which do not encode any protein. Here the HDV ...
Hepatocyte expression of pre-S1 and pre-S2 in relation to hepatitis B virus replication (hepatitis B virus-DNA in serum and HBcAg in the liver), histological activity and hepatitis delta virus superinfection was studied by indirect immunofluorescence on frozen sections of liver specimens from 68 patients with chronic hepatitis B virus infection. All 44 patients with chronic type B hepatitis had...
do not know whether it is due to the effects of toxic compounds or whether it is a genetic association. Whether dietary manipulation will affect the development of obstructive cardiomyopathy remains to be seen; if it does, diagnosis would need to be made early in life. Whatever the aetiology of the cardiomyopathy, the association with tyrosinaemia suggests that caution should be expressed in co...
INTRODUCTION Both hepatitis B virus (HBV) and hepatitis D virus (HDV) infection play an increasingly important role in liver diseases. The main objective of this study was to investigate the socio-epidemiological, laboratory and radiological aspects of both HBV and HDV infection near the Iranian border of Turkey. MATERIAL AND METHODS The study included 3352 patients with HBV and HDV infection...
سابقه و هدف: عامل ویروس هپاتیت دلتا (hepatitis delta virus) یک ویروس دارای rna ناقص است که همراه با (hbv)hepatitis b virus ایجاد عفونت می نماید. در سراسر دنیا 15 میلیون نفر آلوده به hdv می باشند. در مطالعات انجام شده در ایران و کشورهای مختلف، آمارهای متفاوتی در مورد شیوع hdv بیان شده است. این تحقیق به منظور تعیین شیوع hdv در شهر ساری و بررسی عوامل مرتبط با آن انجام شد.مواد و روش ها: این مطالعه ...
Hepatitis delta virus (HDV) packaging requires prenylation of the HDV large protein (p27), as well as a direct protein-protein interaction between HDV proteins and hepatitis B virus (HBV) envelope protein domains. To investigate this interaction, we have analysed the binding capacity of baculovirus-expressed delta p24 and p27 proteins to synthetic peptides specific for the HBV envelope. Althoug...
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