نتایج جستجو برای: delayed graft function

تعداد نتایج: 1371189  

2010
Christian Denecke Damanpreet Singh Bedi Xupeng Ge Irene Kyung-eun Kim Anke Jurisch Anne Weiland Antje Habicht Xian C. Li Stefan G. Tullius

Elderly organ transplant recipients represent a fast growing segment of patients on the waiting list. We examined age-dependent CD4(+) T-cell functions in a wild-type (WT) and a transgenic mouse transplant model and analyzed the suppressive function of old regulatory T-cells. We found that splenocytes of naïve old B6 mice contained significantly higher frequencies of T-cells with an effector/me...

Journal: :Current opinion in organ transplantation 2010
E R Pieter Hoogland Maarten G J Snoeijs L W Ernest van Heurn

PURPOSE OF REVIEW The purpose of the present review is to describe the current kidney preservation techniques for donors after cardiac death and to give insight in new developments that may reduce warm ischemia times and therefore improve graft function after transplantation. RECENT FINDINGS There is still a general reluctance to use donors after cardiac death for kidney donation and transpla...

Journal: :Archives of surgery 2000
P J Healey R McDonald J H Waldhausen R Sawin D Tapper

HYPOTHESIS We hypothesized that improved outcomes following renal transplantation in high-risk infants and small children primarily are due to advances in immunosuppression and accurate diagnosis of rejection. Optimizing renal allograft perfusion is critical to achieving good early graft function and decreasing early graft loss. DESIGN Twenty-eight consecutive recipients (weighing <20 kg) of ...

Journal: :The American journal of pathology 2010
Giuseppe Castellano Rita Melchiorre Antonia Loverre Pasquale Ditonno Vincenzo Montinaro Michele Rossini Chiara Divella Michele Battaglia Giuseppe Lucarelli Gennaro Annunziata Silvano Palazzo Francesco Paolo Selvaggi Francesco Staffieri Antonio Crovace Mohamed R Daha Maurice Mannesse Sandra van Wetering Francesco Paolo Schena Giuseppe Grandaliano

Ischemia-reperfusion injury is the major cause of delayed graft function in transplanted kidneys, an early event significantly affecting long-term graft function and survival. Several studies in rodents suggest that the alternative pathway of the complement system plays a pivotal role in renal ischemia-reperfusion injury. However, limited information is currently available from humans and large...

Journal: :Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 2015
Alexey G Stolyar Ludmila N Budkar Svyatoslav I Solodushkin Irina F Iumanova

OBJECTIVES We analyzed different donor characteristics to determine those that significantly affect patient and graft outcomes after kidney transplant. MATERIALS AND METHODS We conducted a retrospective analysis of patients who had received kidney transplants at our institution between 1990 and 2011 from deceased-donors. We tracked these patients until the end of 2014. Using univariate and mu...

Journal: :The Journal of surgical research 2010
Andreas Karachristos Argenis Herrera Nicole M Sifontis Justin Darrah Craig Baribault Iris Lee Stephen H Leech Serban Constantinescu John Gaughan Ashokkumar Jain Patricio Silva John A Daller

BACKGROUND The purpose of this study was to evaluate long-term outcomes in high risk renal transplant recipients over 60 years of age compared with those younger than 60 years of age. MATERIALS AND METHODS We analyzed outcomes in 131 consecutive renal transplant recipients at our institution between November 2001 and December 2007. Primary outcomes included incidence of delayed graft function...

اعلاتاب, سودابه , پورمند, غلامرضا ,

Thymoglobulin is a purified polyclonal immunoglobulin that has been used widely over the last decades in the prevention and treatment of rejection following renal transplantation. This immunoglobulin works against human thymocytes. Since thymoglobulin does not contain the nephrotoxic properties therefore it can be used in induction therapy especially in patients with higher risk of graft reject...

Journal: :Genetics and molecular research : GMR 2014
W X Liang M J Cai L Jiang Y Q Xie W L Yuan H Zhang

We investigated the ultrasonic imaging characteristics of transplanted kidneys with delayed graft function (DGF). Ultrasonography was performed in 44 patients after kidney transplantation, and a time-intensity analysis was performed to compare the differences between patients with normal graft function (NGF) and those with DGF. Compared with the NGF group, the DGF group had earlier arrival time...

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