The intravenous administration of gadopentetate dimeglumine (GD) is relatively safe and rarely causes systemic toxicity in the course of routine imaging studies. However, the general safety of intrathecal GD has not been established. We report a very rare case of an overdose intrathecal GD injection presenting with neurotoxic manifestations, including a decreased level of consciousness, global ...

conclusions bis-guided management may not be superior to routine monitoring protocols to prevent awareness as well as hemodynamic changes during general anesthesia in patients undergoing abdominal surgeries. results the overall incidence of awareness in the bis and routine monitoring groups were 5.5% and 4.1%, which was not significantly different. there were no significant differences in hemod...

A case of lymphomatous meningoencephalitis in a 23 year old Brazilian patient with HTLV-I/II associated myelopathy is reported. The patient was admitted to the hospital with a clinical picture of decreased consciousness level, stiffness of the neck and previous diagnosis of myeloneuropathy. CSF examination showed lymphocytosis with blastic cells and antibodies against HTLV-I/II.

A 70-year-old Japanese man was admitted to hospital because of decreased consciousness due to type II respiratory failure. Severe hypothyroidism was diagnosed and considered to be associated with hypoventilation due to respiratory muscle dysfunction and sleep apnea syndrome. His status was improved partially by replacement of thyroid hormone. Despite maintaining a euthyroid state, improvement o...

Transient loss of consciousness associated with focal temporal lobe seizures is a complex phenomenon with life-threatening repercussions. In this issue of Neuron, Motelow et al. (2015) describe decreased cholinergic drive and suppressed subcortical arousal in seizures as a novel mechanism for impaired cortical function.

The purpose of this study was to compare nondysfunctional children with and without handwriting difficulties for an examination of grip and hand preference. Additionally, in the group of children with handwriting difficulties, the children with decreased proprioceptive-kinesthetic finger awareness were compared with the children without such a decrease. The results suggest that children with ha...

Disorders of consciousness are neurological conditions associated with low levels of functioning which pose a serious challenge to public health systems. The current study aimed to examine longitudinal changes in functioning in patients with disorders of consciousness and to identify associated biopsychosocial factors using the International Classification of Functioning, Disability, and Health...

OBJECTIVE Increasing use of methadone in withdrawal programs has increased methadone poisoning in children. This research aimed to study the causes of incidence of poisoning in children and its side-effects. MATERIALS & METHODS In this research, The hospital records of all methadone-poisoned children referred to Hamadan's Be'sat Hospital from June 2007 to March 2013, were studied. Children wi...

BACKGROUND Critical care patients are at higher risk for untreated pain. Pain has persistent and untreated effects on most of the body systems and results in development of complications, chronic pain, and increased length of stay. The aim of this study was to determine the effects of the implementation of a pain management program on the length of stay in patients with decreased level of consc...