BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is becoming a leading cause of chronic liver disease. Hepatocellular carcinoma (HCC) is one of its complications. Although the pathophysiology is unclear, it is reasonable to expect that cryptogenic cirrhosis related HCC (cryptogenic HCC) behaves differently to other types of HCC. This study prospectively compared patients with cryptogenic HC...

Background and Aims: Portal Hypertension (PHT) is a major cause of morbidity mortality in pediatric liver diseases. We aimed to study patients` characteristics outcome adolescent population presenting with PHT. Methods: Prospectively collected clinic database from January 2014 December 2022 was analysed identify (10-19 years age group) features Results: Total 125 patients reviewed. Male were 79...

BACKGROUND Acquired deficiencies of certain complement proteins and impaired opsonisation activity have been implicated in the pathogenesis of the increased susceptibility to infections of patients with alcoholic cirrhosis. METHODS Serum concentrations of C3 and C4, plasma concentrations of C3bc, C9, and the terminal C5b-9 complement complex (TCC), and haemolytic complement activity (classic ...

We report a case of cryptogenic liver cirrhosis likely due to khat consumption diagnosed in the setting of chronic hypertension and giving the appearance of atypical superimposed preeclampsia.

BACKGROUND There is increasing evidence that proton pump inhibitors (PPIs) increase the rate of infections in patients with decompensated cirrhosis. AIMS To estimate the extent to which proton pump inhibitors (PPIs) increase the rate of infections among patients with decompensated cirrhosis. METHODS We conducted a retrospective propensity-matched new user design using US Veterans Health Adm...

BACKGROUND Cirrhosis and severe sepsis are factors associated with increased mortality in intensive care unit (ICU), but chronic hepatitis C (CHC) has been less studied in ICU. The aim of this study was to analyze the impact of CHC on the mortality of cirrhotic patients admitted to ICU according to severe sepsis and decompensated cirrhosis. METHODS We carried out a retrospective study based o...

Elderly patients with diabetes, hypertension and obesity are at risk of severe course the novel coronavirus infection COVID-19. Patients chronic liver disease also high death due to SARS-CoV-2. Case report . Patient D., 65 years old, since 2010, was observed for Child-Pugh class B-C cirrhosis mixed etiology (alimentary metabolic), type 2 diabetes. He hospitalized on May 17, 2020 shortness breat...

INTRODUCTION Liver cirrhosis (LC) is a relatively frequent cause of death in the United States accounting for more than 27,000 deaths per year as of 2002 (1). Medical complications are frequent in patients with LC and more so when the liver disease becomes decompensated (2). LC is considered decompensated when patients develop at least one complication of the disease (hepatic encephalopathy, ga...