Alternative splicing is an important component of tumorigenesis. Recent advent of exon array technology enables the detection of alternative splicing at a genome-wide scale. The analysis of high-throughput alternative splicing is not yet standard and methodological developments are still needed. We propose a novel statistical approach-Dually Constrained Correspondence Analysis-for the detection...

A novel method for the rapid screening of degradation products derived from nerve agents by matrix-assisted laser desorption ionization time-of-flight mass spectrometry is described. Five standard products were selected as model compounds, including isopropyl methylphosphonic acid (IMPA), pinacolyl methylphosphonic acid (PMPA), ethyl methylphosphonic acid (EMPA), isobutyl methylphosphonic acid ...

The cross-correlation between the China Securities Index 300 (CSI 300) index futures and the spot markets based on high-frequency data is discussed in this paper. We empirically analyze the cross-correlation by using themultifractal detrended cross-correlation analysis (MF-DCCA), and investigate further the characteristics of asymmetry, frequency difference, and transmission direction of the cr...

There is ample evidence that Islamic stock markets perform differently from conventional markets, particularly when economic policy uncertainty (EPU) or any other such as geopolitical present. Considering this context, paper examines the US EPU’s cross-correlation with both and perspective of multifractality. Daily market prices five main countries are considered: US, Thailand, Indonesia, Pakis...

Abstract We present a study on portfolio investments in financial applications. describe general modeling and simulation framework the impact use of different metrics to measure correlation among assets. In particular, besides traditional Pearson’s correlation, we employ Detrended Cross-Correlation Analysis (DCCA) Partial (DPCCA). Moreover, novel allocation scheme is introduced that treats asse...

This study surveyed the exposure to pesticides among farmers in Chiang Mai’s highland agricultural area. Ethnic Hmong farmers, living in Baan Buak Jan, Mae Rim District, Chiang Mai Province were selected as the study population. Pesticide-specific urinary metabolites were used as biomarkers of exposure to a variety of pesticides, including organophosphorus pesticides, synthetic pyrethroids and ...

Particularly in anatomic pathology, the past 2 decades have witnessed a proliferation of tests that are surrogates for selected analytes of predictive or prognostic interest. Those targets include such moieties as functional hormone receptor proteins and the composition of genes that govern responses to selected growth factors. Common respective examples of those groups are estrogen and progest...