Proteins containing the G protein regulator (GPR) domain bind the major neural G protein Gα(o) in vitro. However, the biological functions of GPR proteins in neurons remain undefined, and based on the in vitro activities of GPR proteins it is unclear whether these proteins activate or inhibit G protein signaling in vivo. We found that the conserved GPR domain protein AGS-3 activates Gα(o) signa...

Over the last few years high-resolution geophysical techniques, in particular ground-penetrating radar (GPR), have been used in agricultural applications for assessing soil water content variation in a non-invasive way. However, the wide use of GPR is greatly limited by the data processing complexity. In this paper, a quantitative analysis of GPR data is proposed. The data were collected with 2...

Objectives To systematically review randomized controlled trials that assessed the effects of Global Postural Reeducation (GPR) on patient-reported outcomes in conditions of the musculoskeletal system. Method An electronic search of MEDLINE (via PubMed), EMBASE, Cochrane CENTRAL, and SciELO was performed from their inception to June 2015. Randomized controlled trials that analyzed pain and pati...

a r t i c l e i n f o At the Late Bronze Age site of Kalavasos-Ayios Dhimitrios in southern Cyprus, the subterranean remains of previously unknown buildings were recently discovered and mapped with ground-penetrating radar (GPR). Though the fine-grained calcareous substrate at the site was not necessarily ideal for GPR—exhibiting a high clay fraction, significant volumetric water content, and s...

ENSCO, Inc. is investigating a novel approach to data fusion of magnetic and ground-penetrating radar (GPR) data to characterize previously detected buried targets. The method exploits a single model of the subsurface to predict both magnetic and GPR data observations. By determining the best single model that constrains both data sets, the optimum identification is computed. Using an a priori ...

BACKGROUND Spindle positioning during an asymmetric cell division is of fundamental importance to ensure correct size of daughter cells and segregation of determinants. In the C. elegans embryo, the first spindle is asymmetrically positioned, and this asymmetry is controlled redundantly by two heterotrimeric Galpha subunits, GOA-1 and GPA-16. The Galpha subunits act downstream of the PAR polari...

During the last decade Ground Penetrating Radar (GPR) has proved its ability to act as a powerful geophysical tool for subsurface investigations. GPR is a more user friendly and cost-effective tool due to recent technological developments. Lower cost and simple operation has increased the practice of GPR in the utility locating market as well as other traditional markets. Deploying GPR methods ...

The gastropyloric receptor (GPR) neurons of the stomatogastric nervous system of the crab Cancer borealis are muscle stretch receptors that can fire in either a spiking or a bursting mode of operation. Our goal is to understand what features of muscle stretch are encoded by these two modes of activity. To this end, we characterized the responses of the GPR neurons in both states to sustained an...

Radioactive sources exist in environments or contexts that influence how they are detected and localised. For instance, the context of a moving source is different from a stationary source because of the effects of motion. The need to incorporate this contextual information in the radiation detection and localisation process has necessitated the integration of radiological and contextual sensor...

Abstract Cost‐effective computing capabilities paved the road to use numerical modeling develop advanced methods and applications of ground‐penetrating radar (GPR). Realistic synthetic data corresponding techniques, respectively, should consider all subsurface above‐ground aspects that influence GPR wave propagation characteristics recorded signals. Critical can be realized in modern tools incl...