melissa (melissa offcinalis l.), a member of a lamiaceae family, is a medical plant. the main most important pharmacological properties can be soothin, strengthening nerve, carminative and memory booster. the presence of heavy metals is one of important environmental stresses that can reduce growth and production of types of reactive oxygen. in the present study, the effect of copper sulfate (c...

abstract background and objective: parkinson's disease (pd) is an age-related neurodegenerative disorder with massive loss of dopaminergic neurons in the substantia nigra pars compacta. l-dihydroxyphenylalanine (l-dopa) substitution is still the gold standard therapy for pd. however, there has been little information available on neuroprotective and regenerative therapies for pd. due to the neu...

one-pot, four-component procedure for the synthesis of a small library of new chiral spiro- oxindolopyrrolidines with high regio-, diastereo- (>99:1 dr), and enantioselectivity (up to 80% ee) is described. in this process, the regio- and stereochemical 1,3-dipolar cycloaddition of azomethine ylides, which were generated insitu by the reaction of isatin derivatives and sarcosin,with optically ac...

introduction: oxidative stress seems to play a critical role in the degeneration of dopaminergic neurons in parkinson’s disease (pd). antioxidant compounds can deactivate and scavenge free radical. olive leaves are considered as a useful source of phenolic compounds. therefore, this study was designed to investigate the effects of methanolic olive leaf extract (ole) on neurobehavioral activity ...

pollen storage could facilitate the date palm hand pollination through saving time and space. the main concern is maintaining pollen viability, which is greatly cultivar dependent and is influenced by storage condition. in this study, to address this issue, the effects of cultivar, storage temperature, and time on pollen germination were investigated. a factorial experiment was laid out in a co...

an efficient and convenient protocol for synthesis of 3-hydroxy-3-indolyl-2-oxindoles and 3,3-diindolyl-2-oxindoles is presented here. the syntheses were achieved selectively under catalysis of liclo4 whereby the products were obtained purely.

abstract background: gastric cancer is a life threatening disease. recent studies have shown that rosa damascene possesses noticeable biological effects on the human body. this study, investigates the anticancer effect of rosa damascena on gastric cancer cell line mkn45. methods: microscopic studies and mtt assay were used to examine morphological alteration, and cell survival of the cancer cel...

in traditional chinese medicine, arsenous compounds, including arsenic trioxide (ato), are often used to treat many diseases, which are safe and effective. recently, studies have indicated that th17– il-17 involved in the pathogenesis and development of asthma. the goal of this study was to investigate the effect and mechanism of ato on asthma, especially the th17– il-17 axis. we used oval bumi...

introduction the main problems relating to water quality for agriculture are salinity, soil infiltration and specific ions toxicity. accumulation of the specific ions from the irrigation water in the plants reduces crop yields. one of the most common specific ions toxicities results from high concentration of chloride (cl) ion. knowledge of the spatial distribution of cl concentration in ground...