BACKGROUND Although cytomegalovirus viral load is commonly used to guide pre-emptive therapy in the post-transplantation setting, few data are available correlating viraemia with clinical endpoints. We therefore investigated the association between cytomegalovirus viral load and mortality in the first year after haemopoietic stem cell transplantation. METHODS In this retrospective cohort stud...

BACKGROUND Cytomegalovirus retinitis is a common AIDS-associated illness, leading to blindness in up to 30% of patients. This study was to investigate the prevalence and clinical management of the cytomegalovirus retinitis associated with AIDS in a large municipality of China. METHODS Clinical and laboratory data from 23 cytomegalovirus retinitis patients (35 eyes) out of 303 hospitalized AID...

Ganciclovir and foscarnet possess substantial activity against cytomegalovirus. Both exhibit dose-limiting toxicity, which reduces their clinical usefulness. We demonstrated synergistic inhibition of cytomegalovirus replication in vitro by ganciclovir and foscarnet. Reduced-dose combination therapy may provide a means to treat patients with cytomegalovirus infection while reducing drug toxicity.

An anti-complement immunofluorescence test utilizing cytomegalovirus immune hamster sera specifically identified cytomegalovirus isolates showing an early, typical cytopathic effect. Inclusion of a control conjugate against adenovirus group antigen permitted correct identification, as adenoviruses, of a few isolates initially suspected of being cytomegalovirus on the basis of cytopathic effect.

Viruses, including human cytomegalovirus (HCMV), reprogram cellular metabolism using host metabolic regulators to support virus replication. Alternatively, in response infection, the can use limit

human cytomegalovirus (hcmv, cmv) is a major infectious complication of renal transplantation. the objective of this survey was to optimize and establish a polymerase chain reaction (pcr) technique for rapid and early detection of cmv disease in renal transplant recipients. in a cross sectional study, a total of eighty-one edta-blood samples were collected as simple nonrandomized (sequential) w...

cytomegaloviurs (cmv) is the most frequent cause of congenital infection in humans. in various parts of the world the prevalence of antibodies to cmv ranges from 40-100%. the prevalence of primary infection with cmv in pregnant iranian women and risk of congenital cmv infection in their neonates are unknown. to determine the prevalence of cmv infection in primiparous pregnant (youner) women and...

conclusions according to the results of this study, quantification of hcmv and ebv observed in this study is high in periodontal tissue samples of severe chronic periodontitis. background although studies focused mainly on the identification of periopathogenic bacteria, recent reports have suggested that various herpes viruses may also be involved in the occurrence and progression of different ...

purpose : to report a patient with branch retinal vein occlusion (brvo) and serologic evidence of primary cytomegalovirus (cmv) infection case report : we have reported a 27-year-old male with a complaint of sudden decrease in right eye vision starting a few days before. results : immunoglobulin g (igg) seroconversion indicated primary cmv infection. conclusion : involvement and obstruction of ...