BACKGROUND Some syphilis patients remain in a serologically active state after the recommended therapy. We currently know too little about the characteristics of this serological response. METHODS We conducted a cohort study using the clinical database from Zhongshan Hospital, Medical College of Xiamen. In total, 1,327 HIV-negative patients with primary, secondary, latent, and tertiary syphil...

background: the present study was performed to develop a scoring system for predicting cure status in patients with cutaneous leishmaniasis (cl). materials and methods: this study included 199 patients with cl from skin diseases and leishmaniasis research center (isfahan, iran). data were collected as longitudinal in each visit of patients. we applied ordinal logistic generalized estimating equ...

BACKGROUND The study on SIMS and SMUS as a whole by Alyaa Mostafa et al showed that after excluding the TVT-S sling, there is no significant difference in patient-reported cure rate and objective cure rate between these two methods. In this paper, we systematically evaluate the relevant data on SIMS-Ajust and TVT-O/TOT and further confirm their safety and effectiveness, providing reliable clini...

BACKGROUND An epidemic strain of Clostridium difficile designated by restriction endonuclease analysis (REA) as group BI has caused multiple outbreaks of severe C. difficile infection (CDI). The treatment response of patients infected with this strain is uncertain. METHODS Clostridium difficile isolates were collected from 2 phase 3 clinical trials comparing fidaxomicin to vancomycin and type...

BACKGROUND Management of patients suffering from tuberculosis (TB) after discharge from hospital plays a critical role in the cure rate of TB. Despite interventions developed by the World Health Organization (WHO) to improve the cure rate, TB remains a worldwide health problem. OBJECTIVE The purpose of the study was to explore and describe the views of professional nurses regarding the low TB...

Background: Tinea versicolor is a common superficial mycosis, which is caused by lipophilic yeasts, malessezia furfur. It is a chronic and recurrent skin disease. It occurs most commonly in young post-pubertal people and in hot and humid climates (North and south provinces of Iran). Objective: Comparison of effects of ketoconazole 2% shampoo (Shafa Lab) with selenium sulfide 2.5% shampoo on tin...

INTRODUCTION Onychomycosis is a fungal infection of the nail unit. Anatomical and physiological characteristics of the nail apparatus impose the need for long-term treatment to achieve complete cure. GOAL The main goal of this project is to study the effectiveness of several treatment protocols for onychomycosis based on Scoring Clinical Index for Onychomycosis (SCIO). MATERIAL AND METHODS ...

One hundred patients with vulvovaginal candidosis were entered in a double-blind trial to compare the effect of six days' local treatment with clotrimazole with that of the same treatment plus 10 days' oral treatment with nystatin. No significant differences were detected in the rate of cure or relapse between the treatment groups. The cure rate was lowest and the relapse rate highest in patien...

In a double-blind study of the treatment of vaginal candidiasis, miconazole nitrate gave a cure-rate of 88 per cent. (29 out of 33) compared with 58 per cent. (21 out of 36) using chlordantoin. Although approximately two-thirds of the patients who responded did so to a 10-day course of treatment, the different rates of cure with these preparations at this stage were not statistically significan...

that reported an objective cure rate of 76%, considerably lower than the 90% reported long-term cure rate for the standard TVT.5 The other widely marketed device, the Mini-Arc, also has inconsistent outcomes with some studies showing cure rates as low as 62%.6 Gynaecologists and urologists need to be aware of these poorer outcomes, for the TVT-Secur and the Mini-Arc in particular. While mini-sl...