The present investigation was carried out to enhance the plant growth and production of curcuminoids and essential oils from turmeric (Curcuma longa) by gamma rays treatments. The plant samples of turmeric were collected from different regions of Kasur, Bannu and Faisalabad, Pakistan. The rhizomes were irradiated with 00 as control, 10, 20, 30, 40, 50, 60, 70, 80, 90 and 100Gy by cobalt 60 sour...

Hydrogenated curcuminoids are the major metabolites of the curcumin and 'CuroWhite' is a unique blend of hydrogenated curcuminoids encapsulated with β-cyclodextrin. There is no particular scientific evidence for the toxicology regarding the hydrogenated curcuminoids, so the present work reports the results of the studies investigating the acute (single dose) and subchronic (repeatedly 90 days) ...

BACKGROUND Several papers described the structure of curcumin and some other derivatives in solid and in solution. In the crystal structure of curcumin, the enol H atom is located symmetrically between both oxygen atoms of the enolone fragment with an O···O distance of 2.455 Å, which is characteristic for symmetrical H-bonds. In the solution, the geometry of the enolone fragment is attributed t...

The purpose of this review is to summarize the pertinent literature published in the present era regarding ulcerogenic effectors, and all available therapeutic concepts in this regard including; different physiological/pathological changes in response to H. pylori infection, nonsteroidal anti-inflammatory drugs (NSAID), bile acids, nitric oxide, copper complexes, acid pump inhibitors, histamine...

Aim: We report the synthesis and biological evaluation of a small library 15 functionalized 3-styryl-2-pyrazolines pyrazoles, derived from curcuminoids, as trypanosomicidal agents. Methods & results: The compounds were prepared via cyclization reaction between corresponding curcuminoids appropriate hydrazines. All derivatives synthesized investigated for their activities. Compounds 4a 4e sh...

Turmeric has been known for centuries as a spice and an important element of traditional medicine. Nowadays, plant-derived compounds are still object extensive scientific investigations aiming at the development novel drugs dosage forms. its most component, curcumin, reveal numerous interesting biological properties, including antioxidant, anti-inflammatory antimicrobial activity. Numerous stud...