Most existing sequence labelling models rely on a fixed decomposition of a target sequence into a sequence of basic units. These methods suffer from two major drawbacks: 1) the set of basic units is fixed, such as the set of words, characters or phonemes in speech recognition, and 2) the decomposition of target sequences is fixed. These drawbacks usually result in sub-optimal performance of mod...

Analysis of circulating tumor cells (CTC) in the peripheral blood of cutaneous melanoma patients provides information on the metastatic process and potentially improves patient management. The isolation by size of epithelial tumor cells (ISET) is a direct method for CTC identification in which tumor cells are collected by filtration as a result of their large size. So far, ISET has been applied...

To assess the predictive and prognostic significance of folate receptor (FR)-positive circulating tumor cells (CTCs) in patients with small cell lung cancer (SCLC) received first-line chemotherapy. Eligible patients with chemotherapy-naïve, unresectable SCLC were enrolled and blood samples were collected. CTCs were enumerated using ligand-targeted polymerase chain reaction (LT-PCR) at baseline,...

Current and 3-year CTC activity disclosures provided by 482 scientists and clinicians Growth in CTC tests and estimated growth over the next 3 years (±% change) End-users' estimates of the costs per patient, for CTC tests CTC detection/enrichment platforms used currently and in 3 years (±% change) Company CTC platforms used currently and over the next 3 years (±% change) CTC parameters or measu...

BACKGROUND Circulating tumor cells (CTC) have been found in patients with metastatic melanoma and are associated with advanced melanoma stage and poor patient outcome. We hypothesize that CTC harbor genomic changes critical in the development of distant systemic metastasis. Here, we present the first genome-wide copy-number aberration (CNA) and loss of heterozygosity (LOH)-based characterizatio...

OBJECTIVE Computed tomography colonography (CTC) is an alternative diagnostic test to colonoscopy for colorectal cancer and polyps. The aim of this study was to determine test characteristics important to patients and to examine trade-offs in attributes that patients are willing to accept in the context of the diagnosis of colorectal cancer. METHODS A discrete choice study was used to assess ...

Chlortetracycline (CTC) is one of only ten antibiotics licensed in the U.S.A. for use as growth promoters for livestock. The widespread use and persistence of CTC may contribute in development of antibiotic-resistant bacteria. The objective of this study was to determine the effect of composting on the fate of CTC residues found in manure from medicated animals. The effect of CTC residues on co...

BACKGROUND Children aged under five years with severe acute malnutrition (SAM) in Africa and Asia have high mortality rates without effective treatment. Primary care-based treatment of SAM can have good outcomes but its cost effectiveness is largely unknown. METHOD This study estimated the cost effectiveness of community-based therapeutic care (CTC) for children with severe acute malnutrition...

Circulating tumour cells (CTC) in patients with metastatic carcinomas are associated with poor survival and can be used to guide therapy. Classification of CTC however remains subjective, as they are morphologically heterogeneous. We acquired digital images, using the CellSearch™ system, from blood of 185 castration resistant prostate cancer (CRPC) patients and 68 healthy subjects to define CTC...