in this study, we examined the role of early acetazolamide administration in reducing the risk of cerebrospinal fluid (csf) leakage in patients with a high risk of permanent csf leakage. in a randomised clinical trial, 57 patients with a high risk of permanent csf leakage (rhinorrhea, otorrhea, pneumatocele or imaging-based evidence of severe skull-base fracture) were analysed. in the experimen...

BACKGROUND Endoscopic techniques have gained popularity for the repair of anterior skull base defects. OBJECTIVE To describe the 10 year experience with endoscopic surgical repair of cerebrospinal fluid (CSF) rhinorrhea in a tertiary medical center. METHODS The files of all patients who underwent endoscopic transnasal CSF leak repair in our institution between 1996 and 2006 were reviewed. ...

Background and Aim: Several surgical techniques have been so far used for treating Cerebrospinal Fluid (CSF) leakage (rhinorrhea) such as using abdominal fat or fascia lata, but these methods have complications such as the presence of several surgeons in variable fields in the operating room or cosmetic complications for donors such as the surgical scar. This study aimed to investigate using bu...

[1] In the article, “Spontaneous cerebrospinal fluid rhinorrhea: A case report and analysis” , which appears in Volume 97, Issue 5 of Medicine, the hospital name for the affiliations appears incorrectly and the affiliations should appear as: First Department of Neurosurgery, Department of Rheumatology, Department of Clinical Laboratory Diagnostics, China-Japan United Hospital of Jilin Universit...

Radioisotopes have been used in the study of the cerebrospinal fluid (CSF) since Sweet and Locksley (7) first used 131I-albumin to determine the forma tion, flow, and reabsorption of CSF in man. Since that time, cisternographic techniques using radionuclides have been used to evaluate CSF dynamics in conditions ranging from the detection of CSF rhinorrhea (2) to communicating hydrocephalus (3)....

This study describes a case of a patient with traumatic rupture of a maxillary sinus retention cyst, which had an interesting clinical presentation of unilateral rhinorrhea, mimicking a CSF leak. The diagnosis was made fortuitously by comparison of a posttraumatic CT brain examination with a CT sinus study performed 1 day earlier.

Cerebrospinal fluid (CSF) leak is one of several complications that can occur after traumatic skull base injury. Although most patients present soon after the injury occurs, some can present years later, with resulting morbidity and the need for additional procedures. We present a case of a patient with a sphenoid sinus CSF leak who presented 12 years after a closed head injury that included a ...

A 46-year-old woman presented with an intermittent nontraumatic cerebrospinal fluid (CSF) left rhinorrhea. A multidetector computed tomographic (MDCT) study was performed to investigate a CSF fistula (Figure). The sphenoidal sinus is prone to CSF leakage, when anatomical variations occur. The basilar expansion is a posterior expansion of the sphenoidal sinus (postsellar). It is considered criti...

References 1. Meurman OH, Irjala K, Suonpaa J, Laurent B. A new method for the identification of cerebrospinal fluid leakage. Acta Otolaryngol 1979;87: 366–9. 2. Oberascher G. Cerebrospinal otorrhea-cerebrospinal rhinorrhea. The Salzburg concept of cerebrospinal fluid diagnosis. Laryngol Rhinol Otol (Stuttg) 1988; 67:375–81. 3. Reisinger PW, Hochstrasser K. The diagnosis of CSF fistulae on the ...

Because of the location, skull-base chordomas often present with headaches and diplopia and sixth and fifth nerve palsies are the most common neurological signs.[1,2] The interval between onset of symptoms and diagnosis of clival chordoma is quite variable, 2.5-4.4 years.[4] The uncommon clinical presentations include: Nasal obstruction, nasal bleeding, and subarachnoid hemorrhage.[3,5] Spontan...