PURPOSE We examined the effects of creatine supplementation on the response to repeated bouts of resistance exercise. METHODS Young men (24.1 ± 5.2 yr) were divided into Creatine (CM, n = 9) and Placebo (PL, n = 9) groups. On day (D) 1 and D15, subjects performed four sets of bicep curls at 75% 1-RM to concentric failure. On D8-D13, subjects consumed either 20g/d creatine monohydrate or place...

Address correspondence to Dr Adel K. Afifi, Division of Child Neurology, Department of Pediatrics, University of Iowa Hospitals and Clinics, Iowa City, IA 52242. Asymptomatic elevation of creatine kinase (CK) was first reported by Rowland, who proposed to call the condition &dquo;high serum enzymes, cause undetermined.&dquo; In 1980, Rowland et al2 coined the term &dquo;... idiopathic hyperCKem...

Background: Both creatine kinase (CK) and/or lactate dehydrogenase (LDH) mutually are elevatedsignificantly in many tumors. This study hypothesizes that LDH was evaluated as a prognostic factor forsurvival time patients with terminal cancer (PTC). Additionally, CK considered valuable assessingprognosis of advanced patients. aimed to estimate the change CK/LDH levelsin different types comparing ...

Macro creatine kinase (CK, EC 2.7.3.2) and macro lactate dehydrogenase (LD, EC 1.1.1.27) were both present in the serum of a 70-year-old woman with myocardial infarction. This interfered with the interpretation of the CK and LD isoenzyme analyses. Gel filtration and immunoprecipitation showed that the macro CK consisted of IgG and CK and the macro LD of IgG and LD. The IgG in this patient bound...

A 20-year-old man was found to have high plasma creatine kinase (EC 2.7.3.2) activity in association with a rhabdomyosarcoma of the prostate. There was a very high proportion of the MB isoenzyme. Clinical findings and changes in creatine kinase activity with time showed that this increase was not ascribable to myocardial disease. We believe that the high proportion of CK-MB, confirmed by a comb...

introduction: cardiac preconditioning represents the most potent and consistently reproducible method of rescuing heart tissue from undergoing irreversible ischemic damage. the aim of the present study was to evaluate oxytocin (ot) induced cardioprotection and its signaling pathways on lactate dehydrogenase (ldh) and creatine kinase-mb isoenzyme (ck-mb) in the anesthetized rats. methods: eighty...

Background: Hypothyroidism is characterized by a decline in basal metabolic rate which can lead to glycogen build up and decreased enzyme activity energy synthesis other regulatory systems. Thyroid hormones have number of key targets including skeletal muscle. Thus, hypothyroid patients altered glycolysis, glycogenolysis mitochondrial metabolism an impact on muscle function. Timely assessment b...

We studied variations in the activity of total creatine kinase (CK; EC 2.7.3.2) and of CK-B in maternal and cord-blood samples, comparing data obtained for vaginal and cesarean births. CK-B activity was determined with an immunoinhibition assay. In all cases, there was a significant postpartum increase in total CK and in CK-B activity in maternal sera, whereas cord-blood samples showed no signi...