نتایج جستجو برای: cox models

تعداد نتایج: 943575  

انتظار مهدی, رسول, زارعان, الهه, محمودی, محمود, یاسری, مهدی,

Background and Aim: Gastric cancer is one the most common gastrointestinal tract cancers in Iran, with East-Azerbaijan Province ranking second in the country. The objectives of this research were to determine the feasibility of using cure models in survival analysis and factors affecting short-term and long-term patient survival rates using the mixture cure cox model. Materials and Methods:...

حسینی, مصطفی, زراعتی, حجت, شیخ فتح الهی, محمود, قدیمی, محمود رضا, محمد, کاظم, محمودی, محمود,

Background and Aim: The most common cancer in Iran is digestive system cancer, the highest incidence of which is reported from the Caspian Sea littoral. This study aimed to determine factors affecting the survival of patients with gastrointestinal cancer using the Cox and parametric models the 2 models were compared. Materials and Methods: This survey was a prospective study conducted between 1...

امیدی, طاهره, روشنایی, قدرت اله, پورالعجل , جلال, فردمال, جواد ,

Introduction & Objective: Cox model is a common method to estimate survival and validity of the results is dependent on the proportional hazards assumption. K- Nearest neighbor is a nonparametric method for survival probability in heterogeneous communities. The purpose of this study was to compare the performance of k- nearest neighbor method (K-NN) with Cox model. Materials & Methods: This ...

Several studies point to an important function of cyclooxygenase (COX) and prostaglandin signaling in models of synaptic plasticity which is associated with N-methyl-D-aspartate receptors (NMDARs). Cyclooxygenase gene is suggested to be an immediate early gene that is tightly regulated in neurons by NMDA dependent synaptic activity. Nonsteroid Antiinflammatory Drugs (NSAIDs) exert their antiinf...

Several studies point to an important function of cyclooxygenase (COX) and prostaglandin signaling in models of synaptic plasticity which is associated with N-methyl-D-aspartate receptors (NMDARs). Cyclooxygenase gene is suggested to be an immediate early gene that is tightly regulated in neurons by NMDA dependent synaptic activity. Nonsteroid Antiinflammatory Drugs (NSAIDs) exert their antiinf...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه صنعتی شیراز - دانشکده علوم پایه 1392

در حال حاضر مهارکننده های انتخابی cox-2 توجه زیادی را در طراحی داروهای ضدالتهاب غیر استروئیدی (nsaids) به خود جلب کرده اند زیرا آن ها عاری از اثرات جانبی معمول nsaidsهای کلاسیک اند. تحقیق پیش رو بر طراحی مهارکننده های جدید انتخابی cox-2 متمرکز است. ابتدا مدل های سه بعدی آنزیم های cox با مدل سازی هم سانی ساخته شدند. به منظور ساختن مدل های هم-سانی coxs، توالی های آمینواسیدی coxs از وب سایت ncbi...

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