BACKGROUND A subset of patients hospitalized with acute heart failure experiences worsening clinical status and requires escalation of therapy. Worsening heart failure is an end point in many clinical trials, but little is known about its prevalence in clinical practice and its associated outcomes. METHODS AND RESULTS We analyzed inpatient data from the Acute Decompensated Heart Failure Natio...

mulibrey nanism is a rare autosomal recessive syndrome caused by a mutation in the trim37 gene with severe growth retardation and multiple organ involvement. early diagnosis is important because 50% of the patients develop congestive heart failure owing to constrictive pericarditis, and this condition plays a critical role in the final prognosis. a 37-year-old female patient presented with symp...

BACKGROUND Short-course antibiotic regimens, ranging in duration from a single dose to 3 days, are the current standard of care for the treatment of acute lower urinary tract infections (UTIs) in adult women. Despite multiple small randomized, controlled trials (RCTs) showing no difference in efficacy between short-course (</=3 days) and long-course (7-14 days) therapy in children, concerns abo...

the present review classifies and describes the multifactorial causes of anterior cruciate ligament (acl) surgery failure, concentrating on preventing and resolving such situations. the article particularly focuses on those causes that require acl revision due to recurrent instability, without neglecting those that affect function or produce persistent pain. although primary acl reconstruction ...

conclusions abnormal transaminases and uric acid levels are seen in ahf patients. increased ast levels may be a predictor of the need for inotrope during hospital course in these patients. patients and methods a total of 100 patients (aged 16 - 90 years, 60% men) admitted with ahf were enrolled. lfts and uric acid levels were assessed on first day and before discharge, and patients were followe...

Heart failure is an emerging epidemic owing to the growing and ageing population. As such, novel educational programmes for physicians develop professional competence in all aspects of care patients with acute and/or chronic heart are needed.

Many students at German universities have difficulties to cope with the introductory courses on theoretical computer science, which results in very high dropout and failure rates. In the past years we have experimented with a variety of improvements to the theory course held at the University of Potsdam, Germany. During last winter semester we improved the setup of the course by taking into acc...

The inclusivity of all students in the University Economics programme is danger due to a high failure rate first-year mathematics course. This study investigates whether participation bridging course, and what aspects it, can contribute equal opportunities increased Mathematics for Economists henceforth reduce rate. It adds meager European literature on remedial course effectiveness. Through us...

Dogs given 920 cGy of total body irradiation (TBI) followed by autologous marrow infusion uniformly achieve sustained hematopoietic reconstitution. We have previously shown that administration of the anti-MHC class II monoclonal antibody (MoAb) H81.98.21 (IgG2a) at 0.6 mg/kg/d immediately after transplantation results in delayed graft failure. A second noncrossblocking anti-MHC class II MoAb, B...

BACKGROUND The pathomechanism of acute hepatorenal syndrome (HRS), a particular form of acute renal failure that occurs in the course of acute liver injury, is still poorly understood. The aim of our study was to estimate the influence of the activation and inhibition of the nitric oxide pathway on the water/sodium balance and development of acute renal failure in the course of HRS. MATERIAL ...