highly efficient vector, a nonimmune population, and mining conditions that encouraged both vector breeding and malaria transmission fueled recurrent epidemics of malaria, which apparently started in the 1940s or early 1950s; 80% of the cases were P. falciparum. In 1955, public health authorities in Pailin began distributing chloroquine to workers daily; later, the frequency was reduced to twic...

In this study, three common drugs (Cipram®, Panadol extra ®, Xenical®) were investigated. The study involved analyzing the above drugs using the portable NIR spectroscopy. Ten adulterated tablets of each of the above drugs were tested along with ten genuine tablets and other ten placebo tablets which represents another adulterated source for all drugs. Chemometrical Algorithms like Principal Co...

BACKGROUND Good-quality artemisinin drugs are essential for malaria treatment, but increasing prevalence of poor-quality artemisinin drugs in many endemic countries hinders effective management of malaria cases. METHODS To develop a point-of-care assay for rapid identification of counterfeit and substandard artemisinin drugs for resource-limited areas, we used specific monoclonal antibodies a...

Substandard, Spurious, Falsely-Labelled, Falsified and Counterfeit (SSFFC) drugs are an emerging public health concern in India. With one of the huge pharmaceutical sectors in the world, India has a varied prevalence of SSSFC drugs ranging from 0.04% to 34% according to various studies. Apart from severe health consequences, SSSFC drugs also weaken community's trust in the health care system. I...

Most of the counterfeit medicines are manufactured in non good manufacturing practices (GMP) conditions by uncontrolled or street laboratories. Their chemical composition and purity of raw materials may, therefore, change in the course of time. The public health problem of counterfeit drugs is mostly due to this qualitative and quantitative variability in their formulation and impurity profiles...

The availability of counterfeit and poor quality drugs contribute to resistance and erroneous efficacy study results as well as directly affecting the health of individuals. This report describes the importance of drug quality monitoring as part of a comprehensive disease surveillance program.