OBJECTIVE To establish reference concentration intervals for salivary cortisol in healthy children, in the morning and in the afternoon, investigating factors that interfere with the concentration measured and the possibility that circadian rhythms are present. METHODS A controlled observational study was carried out with 91 children aged 45 days to 36 months, selected at random and living in...

Caspian kutum fish (Rutilus frisii) wild broodstocks were caught by gillnet during their upstream migration and subjected to short-time confinement stress and their physiological responses have been examined. Thirty fish (average weight of 1217.6 g) were divided into three experimental groups CO (control), OV (ovaprim) and CO+OV (cortisol+ovaprim) and placed into rearing tanks (10 fish tank-1; ...

James I. %Vessel, B.S.; and Brandon Taylor, B.S. G lucocorticoids have been recognized to play an important role in lung development in utero.’ The identification of specific receptors for cortisol in both the cytosol and nuclear fraction of fetal lung homogenates supports the concept that the lung is an important target tissue for this steroid.2.3 Administration of cortisol to rabbit fetuses a...

This study examined the effects of dexamethasone treatment on basal hypothalamo-pituitary-adrenal (HPA) axis function and HPA responses to subsequent acute hypoxemia in the ovine fetus during late gestation. Between 117 and 120 days (term: approximately 145 days), 12 fetal sheep and their mothers were catheterized under halothane anesthesia. From 124 days, 6 fetuses were continuously infused in...

The ontogeny and developmental control of plasma leptin concentration in the fetus are poorly understood. The present study investigated plasma leptin concentration in chronically catheterized sheep fetuses near term, and in neonatal and adult sheep. The effect of glucocorticoids on plasma leptin in utero was examined by fetal adrenalectomy and exogenous cortisol or dexamethasone infusion. In i...

Ten patients with stable renal function two years after transplantation had their sole immunosuppressive treatment (oral prednisolone 10 mg daily) withdrawn by reducing the daily dose by 1 mg at monthly intervals. Plasma prednisolone concentration, cortisol concentration, creatinine clearance, and serum creatinine concentration were measured in all patients, and the adrenal response to corticot...

We have examined the effect of intraoperative and postoperative (4 h) continuous spinal anaesthesia for colonic surgery on the postoperative glucose, lactate and cortisol responses. Twenty-one patients were studied; the first group (control) received general anaesthesia, the second group (extradural) an extradural block (T4-S5) and the third group (spinal) a continuous spinal block (T4-S5). Pla...

OBJECTIVE To describe changes in WBC counts, plasma cortisol concentration, and fecal parasite shedding of dogs housed in an animal shelter and determine the effects of daily petting sessions on these variables. DESIGN Hybrid prospective observational and experimental study. ANIMALS 92 healthy dogs newly arrived to an animal shelter and 15 healthy privately owned dogs (control group). PRO...

In severely ill patients low concentrations of the corticosteroid binding globulin are typically found; the aim of this study was to quantify directly free bioactive cortisol concentrations in the sera of postoperative cardiosurgical patients. Serum samples of 12 consecutive patients undergoing aortocoronary bypass surgery taken preoperatively and on the postoperative days 1 to 4 were analyzed....