نتایج جستجو برای: corticotropin hormone

تعداد نتایج: 144660  

Journal: :Journal of neuropathology and experimental neurology 2013
Daniel J van Wamelen N Ahmad Aziz Juan Zhao Rawien Balesar Unga Unmehopa Raymund A C Roos Dick F Swaab

In Huntington disease (HD), hypothalamic neuropeptidergic systems are not equally affected at the peptide and mRNA levels. Because prohormone convertases (PCs) are critically involved in the conversion of propeptides into their active forms, we postulated that a decrease in PC expression may underlie these discrepancies. Therefore, we assessed the expression of PC1/3 and PC2 in the hypothalamic...

2013
Ivo Heitland Lucianne Groenink Elisabeth Y. Bijlsma Ronald S. Oosting Johanna M. P. Baas

The ability to identify predictors of aversive events allows organisms to appropriately respond to these events, and failure to acquire these fear contingencies can lead to maladaptive contextual anxiety. Recently, preclinical studies demonstrated that the corticotropin-releasing factor and serotonin systems are interactively involved in adaptive fear acquisition. Here, 150 healthy medication-f...

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