The development of crural Pacinian corpuscles was explored in neonatal mutant mice lacking nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT3) or neurotrophin-4 (NT4), or their cognate Trk receptors. Deficits of the corpuscles and their afferents were greatest in NT3, less in BDNF, and least in NT4 null mice. Deletion of NGF or p75(NTR) genes had little or ...

Mitsuo Tanno (丹 野 三 男) From Prof. F. Nakazawa's Internal Clinic, Medical Department, Tohoku University, Sendai (Received for publication, April 9, 1956) From the studies of Morawitz1) and Warburg2) it is evident that , like other tissues or cells, the blood corpuscles taken out of living bodies but kept at blood temperature exercise, as one of their vital phenomena, respiration by themselves, c...

a. The blood of apparently normal animals undergoes considerable variations within physiological limits. b. After a loss of blood the regeneration is more rapid if there has been a transfusion of an artificial serum. c. Regeneration after transfusion is less rapid during the first half of the regeneration period than during the second half. d. The regenerative processes once stimulated into act...

The absorption of amboceptor by corpuscles is rapid, a considerable amount being absorbed in as short a period as fifteen seconds. In the sensitization of corpuscles, the amount of amboceptor absorbed by the different corpuscles is not uniform, the inequality depending on the time taken in obtaining an even distribution of the corpuscles through the diluted immune serum. Amboceptor absorption i...

The presence or absence of type-VI collagen in mechanoreceptors in the lips and palate of the mouse and gerbil was assessed histochemically. When fresh palatine mucosae and the lips of mice were incubated in 20 mM ATP solution, numerous fibrous long spacing fibers with a periodicity of 100 nm appeared in the interlamellar spaces of Meissner's corpuscles, simple lamellated corpuscles, and the pe...

Human red blood corpuscles contain many antigens besides the A and B factors, those of greatest clinical importance being the Rb factors. The first of these factors was discovered by Landsteiner and Wiener (1940), and was so called because a similar factor is present in the corpuscles of the Rhesus monkey. This factor is demonstrable in the corpuscles of 85 per cent, of Europeans an^ white Amer...