Background Photorefractive keratectomy (PRK) is at risk of serious complications such as corneal ectasia, which can reduce corrected distance visual acuity. The rate of complications of PRK is higher in patients with atypical topography. Objective To determine the outcomes of photorefractive keratectomy in patients with atypical topography. Methods This cross-sectional study was done in 201...

Keratoconus, which is a degenerative collagen disorder, affects approximately 1 in 2000 individuals in the general population.1,2 This corneal ectasia usually presents at late puberty and is shown to progress for approximately 10–20 years.3 Keratoconus results in changes within the ordered distribution of collagen fibrils in the cornea, leading to loss of stiffness in the stromal structure.1 Th...

Ultra-high resolution optical coherence tomography (UHR-OCT) can image the corneal epithelium and Bowman's layer and measurement the thicknesses. The purpose of this study was to validate the diagnostic power of vertical thickness profiles of the corneal epithelium and Bowman's layer imaged by UHR-OCT in the diagnosis of sub-clinical keratoconus (KC). Each eye of 37 KC patients, asymptomatic fe...

PURPOSE To present the Tomographic and Biomechanical Index (TBI), which combines Scheimpflugbased corneal tomography and biomechanics for enhancing ectasia detection. METHODS Patients from different continents were retrospectively studied. The normal group included 1 eye randomly selected from 480 patients with normal corneas and the keratoconus group included 1 eye randomly selected from 204...

doi:10.3928/1081597X-20110412-01 C orneal ectasia remains a rare but potentially devastating complication after LASIK. In the past, treatment options have been limited; however, exciting advances have expanded our alternatives for visual rehabilitation. Any effective management strategy for ectasia after LASIK will encompass three fundamental principles: 1) halt the ectatic process; 2) reduce c...

Keratoconus is the most common ectatic condition affecting the cornea in the middle-aged population, which has been known for more than a century till now [1]. It is most commonly diagnosed in the late teens or early twenties, but may appear in children [2,3]. The widely used corneal topography and now tomography are the cornerstones for diagnosis and classification of corneal ectasia, speciall...

Collagen cross-linking (CXL) is a relatively new conservative approach for progressive corneal ectasia, which is able to strengthen corneal tissue reforming new covalent bonds. Subjective and objective results following this method seem to be promising. In recent years, newer CXL protocols have been developed to perform more effective and less invasive procedures. The increasing diffusion of CX...

PURPOSE To assess the long-range outcomes of photorefractive keratectomy (PRK) using functional and topographic criteria in myopic eyes with suspected keratoconus. SETTING Rothschild Foundation, Paris, France. DESIGN Retrospective interventional case series. METHODS Eyes of patients classified as keratoconus suspects or keratoconus by the Corneal Navigator software of the OPD-Scan II devi...

PURPOSE To measure the lower tear meniscus dynamics with Fourier domain-optical coherence tomography (FD-OCT) in keratoconus patients without dry eye findings to evaluate the effects of the corneal ectasia on lower tear meniscus parameters, and to determine the most affected meniscus variable from the corneal ectasia in keratoconus. METHODS Prospective, clinical study. Forty-one eyes of 25 ke...

The introduction of corneal cross-linking (CXL) has changed the landscape of treatment and management of keratoconus and ectasia after refractive surgery. Previously, treatment options provided only temporary visual rehabilitation without limiting disease progression. Keratoconus and ectasia resulted in significant vision-related reduction in quality of life and a substantial lifetime economic ...