Five pairs of rabbit corneas were stored for two weeks at 4 degrees C, one of each pair in K-Sol medium, and one in McCarey-/Kaufman (M-K) medium. After transplantation all penetrating keratoplasty grafts became clear and thin. Endothelial cell loss was significantly less in the K-Sol stored corneas. Another five pairs of corneas were stored for two weeks in K-Sol or three days in M-K medium. A...

Microkeratome-assisted anterior lamellar keratoplasty has emerged as a surgical option for conditions affecting the clarity of the outer 200 mum of the cornea. Herein we describe the outcome of a simple procedure in which the excimer laser can be used to augment deep tissue removal after both recipient bed and donor graft are prepared with the microkeratome. Our noncomparative interventional ca...

We conducted a retrospective study of 107 penetrating keratoplasties in 99 eyes (99 patients) performed from 1970 to 1979 at the Wills Eye Hospital. The follow-up periods ranged from one to 12 years (median, three years). Overall, 86 of the 107 transplants (80%) remained clear and 63 eyes (59%) achieved good to excellent visual acuities (20/60 or better). Preoperative vascularization was not a ...

in addition to graft clarity, an acceptable refractive error is essential to consider a corneal transplant successful. the most common complication of penetrating keratoplasty (pk) is postkeratoplasty astigmatism which can result in decreased visual acuity, anisometropia, and mono-ocular diplopia. these complications can cause patient dissatisfaction, in spite of a successful transplant. intrao...

PURPOSE To study the role of mimecan, a member of the small leucine-rich proteoglycans (SLRPs) gene family and one of the major components of the cornea and other connective tissues, mice that lack a functional mimecan gene were generated and characterized. METHODS Mimecan-deficient mice were generated by gene-targeting using standard techniques. Mice were genotyped by Southern blot analysis....

Background & Aims: This study was carried out to determine the leading indications for corneal transplantation in Kerman province. Methods: Medical records of 186 patients underwent corneal transplantation during 3 years (2004-2006) in Shafa Medical Center were evaluated retrospectively. The initial diagnosis and causes of corneal grafting were recorded. Infectious keratitis (Bacterial, Fungal,...

purpose: to report the outcomes of pediatric penetrating keratoplasty (pk) performed in labafinejad medical center, a tertiary referral ophthalmology center, between 2001 and 2012. methods: in this retrospective interventional case series, medical records of all pediatric patients (age≤12 years) who underwent primary pk were reviewed. age at the time of surgery, indications for keratoplasty, po...

PURPOSE To determine definitively the epithelial origin of corneal resurfacing and to elucidate the immunologic mechanisms of epithelial rejection in a murine keratoepithelioplasty (KEP) model. METHODS After corneal epithelial removal and peritomy, donor corneal lenticules were grafted around the limbus (KEP procedure). The process of corneal reepithelialization was observed with 0.25% methyl...

purpose: to evaluate all cases of drug induced angle closure glaucoma cases who presented to feiz hospital, isfahan during 2008-2010. case report: in this retrospective case series, we present 7 cases of drug induced angle closure glaucoma after administration of topiramate. all patients were female. the average age of patients was 33.28 years old (ranging from 19 to 44). with sufficient cornea...

OBJECTIVE To describe the early results of penetrating keratoplasty (PKP) in patients who had previously undergone cultivated limbal epithelium transplantation. METHODS Medical records of patients with limbal stem cell deficiency due to chemical burns who underwent PKP after cultivated limbal epithelium transplantation were reviewed for demographics, primary etiology, type of limbal transplan...