BACKGROUND Anemia is a common, important extraintestinal complication of Crohn's disease. The main types of anemia in patients with Crohn's disease are iron deficiency anemia and anemia of chronic disease. Although patients with Crohn's disease may experience various type of anemia, autoimmune hemolytic anemia (AIHA) in patients with Crohn's disease, especially Coombs-negative AIHA, is very rar...

Using a cohort of C57BL/6 (B6) x (NZB x B6)F1 backcross male mice bearing the Yaa (Y-linked autoimmune acceleration) mutation, we mapped and characterized the NZB-derived susceptibility loci predisposing to the development of autoimmune hemolytic anemia (AHA). Our analysis identified two major loci on NZB chromosome 7 and chromosome 1 linked with Coombs’ anti-erythrocyte autoantibody production...

Using a cohort of C57BL/6 (B6) x (NZB x B6)F1 backcross male mice bearing the Yaa (Y-linked autoimmune acceleration) mutation, we mapped and characterized the NZB-derived susceptibility loci predisposing to the development of autoimmune hemolytic anemia (AHA). Our analysis identified 2 major loci on NZB chromosome 7 and chromosome 1 linked with Coombs antierythrocyte autoantibody production, an...

background: rose bengal is a common test for serologic diagnosis of brucellosis. the aim of this study was to evaluate the agreement rate between modified rose bengal, rose bengal and rapid wright tests for detection of antibody positive serum samples.  methods: c ross section study was designed. 941 serum sample of patients referred to the central medical laboratory of kermanshah, were evaluat...

Case Report Mrs. Vail is group 0, Rh-negative, Duffy-negative; her husband, group 0, Rh-negative, Duffy-positive. Mr. Vall is 0; MsNs; P+; cdE.cde; kk; Fy(a+); Le(a-). Mrs. Vall is 0; NsNs; P+; cde.cde; Kk; Fy(a-); Le(a-); Jk(a+). Baby is 0; NsNs; P+; cde.cde; kk; Fy(a+); Le(a-). Mrs. Vail's pregnancy record is as follows: (1) In 1949, normal. The mother was transfused immediately following thi...