Case–control studies are used often in epidemiologic studies to investigate the association between disease and one or more risk factors. With increasing frequency, the set of risk factors being considered includes genotypes at one or more susceptibility, candidate, or marker loci (see Markers). The goals of association studies will differ, depending on the state of knowledge about a given dise...

I read with interest the article on computerized tests to evaluate psychomotor performance in children with specific learning disabilities (SpLD) by taur and colleagues1. the study was conducted with the aim to compare the performance on a battery of six psychomotor tests of children with SpLD and those without any learning disabilities (controls) using computerized tests. the authors deserve c...

BACKGROUND The case-control design can be used to evaluate the benefit of cancer screening programmes. MATERIALS AND METHODS This paper outlines the main methodological features of the case-control design in this context, and indicates some potential biases. It also reviews the existing case-control literature on mammographic screening. RESULTS Case-control studies consistently indicate a r...