The prevalence, prognosis, clinical presentation, pathophysiology, diagnosis, and treatment of the central sleep apnoea syndrome (CSAS) are reviewed and its relationship with congestive heart failure (CHF) is discussed. Adequately powered trials are needed with survival and health status as end points to establish whether correction of sleep related breathing abnormalities improves the outcome ...

OBJECTIVES The purposes of this study were to determine whether the serum of patients with congestive heart failure (CHF) can induce apoptosis of endothelial cells and to elucidate the underlying mechanisms. Moreover, the effect of the beta-blocker carvedilol was investigated. BACKGROUND Congestive heart failure is associated with impaired endothelial function in the peripheral systemic vascu...

Congestive heart failure (CHF) remains the most common diagnosis made in cardiology wards today. No long-term therapeutic option for end-stage CHF is available except for orthotopic heart transplant. Cellular-based therapy has emerged as a potential new therapy for patients with advanced heart failure. Different cell types are being explored in preclinical and clinical studies with encouraging ...

Congestive Heart Failure (CHF) is a chronic complex syndrome characterized by the inability of heart to support circulation peripheral organs and may cause negative effects on whole human body systems. CHF survivors develop poor adaptation quality life also death. Roy's theory model-based intervention aid in improving patient fulfillment physiological needs, self-concept, role function, interde...

Congestive heart failure (CHF) is the most devastating cardiac sequella of long-standing hypertension. Recent data from the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) have shown the risk of CHF to be twice as high with doxazosin than with chlorthalidone. Although some questions remain regarding the diagnosis and mortality of CHF in the doxazosin arm and...

Congestive heart failure (CHF) is mainly resulted from fibrosis heart. Accumulation collagen in heart fibrosis occurs as result from activity of myofibroblast [1-4]. Myofibroblast is throught to be driven by extracellular stimuli, transformation growth factor β1 (TGF-β1) is one of major player. Interestingly, if the surrounding pathogenic factors are removed, myofibroblast has potential possibi...

he prevalence of congestive heart failure (CHF), chronic schemic heart disease, and diabetes mellitus is increasing in ost societies, and it is not surprising that in most large linical trials of CHF at least 75% of patients have underying ischemic heart disease while approximately 20% to 5% of patients have diabetes (1,2). There is strong evidence hat the presence of diabetes in patients with ...

BACKGROUND Vessel dilator, a 37-amino acid peptide hormone synthesized in the heart, enhances urine flow 4- to 12-fold and sodium excretion 3- to 6-fold in healthy humans. The present investigation was designed to determine whether vessel dilator might have similar beneficial effects in persons with congestive heart failure (CHF). METHODS AND RESULTS Vessel dilator (100 ng/kg body weight per ...

A five-class density histogram with an index named cumulative density was proposed to analyze the short-term HRV. 150 subjects participated in the test, falling into three groups with equal numbers -the healthy young group (Young), the healthy old group (Old), and the group of patients with congestive heart failure (CHF). Results of multiple comparisons showed a significant differences of the c...